Bacterial Infections among Patients with Chronic Diseases at a Tertiary Care Hospital in Saudi Arabia
Infections caused by multi-drug-resistant bacteria in patients with chronic diseases have been associated with high mortality and morbidity. While few reports have evaluated bacterial infections in multiple chronic disease patients, the focus of the current study was to investigate the prevalence of...
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MDPI AG
2022-09-01
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| Series: | Microorganisms |
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| Online Access: | https://www.mdpi.com/2076-2607/10/10/1907 |
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| author | Abdulrahman S. Bazaid Ahmed A. Punjabi Abdu Aldarhami Husam Qanash Ghaida Alsaif Hattan Gattan Heba Barnawi Bandar Alharbi Abdulaziz Alrashidi Abdulaziz Alqadi |
| author_facet | Abdulrahman S. Bazaid Ahmed A. Punjabi Abdu Aldarhami Husam Qanash Ghaida Alsaif Hattan Gattan Heba Barnawi Bandar Alharbi Abdulaziz Alrashidi Abdulaziz Alqadi |
| author_sort | Abdulrahman S. Bazaid |
| collection | DOAJ |
| description | Infections caused by multi-drug-resistant bacteria in patients with chronic diseases have been associated with high mortality and morbidity. While few reports have evaluated bacterial infections in multiple chronic disease patients, the focus of the current study was to investigate the prevalence of bacterial infections and the susceptibility profiles of causative strains among various groups of patients suffering from chronic diseases. Microbiological reports of patients suffering from cancer, diabetes mellitus, cardiovascular diseases, kidney diseases, and skin burns were retrospectively collected from a tertiary hospital in Saudi Arabia. Approximately 54.2% of recruited patients were males, and positive urine was the most prevalent specimen associated with kidney disease patients (25%)<i>. Escherichia coli</i> isolates were predominant among cardiovascular, kidney, and cancer patients. <i>Staphylococcus aureus</i> was commonly detected in diabetics and those with burns. Although resistance patterns varied based on the type of specimens and underlying diseases, <i>Escherichia coli</i> showed limited resistance to colistin, carbapenems, and tigecycline, while <i>S. aureus</i> demonstrated susceptibility to ciprofloxacin, gentamicin, and rifampin. These observations are crucial for clinicians and policymakers to ensure effective treatment plans and improve outcomes in these patients with comorbidity. |
| first_indexed | 2024-03-09T19:45:05Z |
| format | Article |
| id | doaj.art-25afb7e36e4f4b34aceb92a425ee483b |
| institution | Directory Open Access Journal |
| issn | 2076-2607 |
| language | English |
| last_indexed | 2024-03-09T19:45:05Z |
| publishDate | 2022-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Microorganisms |
| spelling | doaj.art-25afb7e36e4f4b34aceb92a425ee483b2023-11-24T01:25:14ZengMDPI AGMicroorganisms2076-26072022-09-011010190710.3390/microorganisms10101907Bacterial Infections among Patients with Chronic Diseases at a Tertiary Care Hospital in Saudi ArabiaAbdulrahman S. Bazaid0Ahmed A. Punjabi1Abdu Aldarhami2Husam Qanash3Ghaida Alsaif4Hattan Gattan5Heba Barnawi6Bandar Alharbi7Abdulaziz Alrashidi8Abdulaziz Alqadi9Department of Medical Laboratory Science, College of Applied Medical Sciences, University of Ha’il, Hail 55476, Saudi ArabiaMicrobiology Unit, Department of Laboratory Medicine and Pathology BB, International Medical Center, Jeddah 21451, Saudi ArabiaDepartment of Medical Microbiology, Qunfudah Faculty of Medicine, Umm Al-Qura University, Al-Qunfudah 21961, Saudi ArabiaDepartment of Medical Laboratory Science, College of Applied Medical Sciences, University of Ha’il, Hail 55476, Saudi ArabiaDepartment of Medical Laboratory Science, College of Applied Medical Sciences, University of Ha’il, Hail 55476, Saudi ArabiaDepartment of Medical Laboratory Technology, Faculty of Applied Medical Sciences, King Abdulaziz University, Jeddah 21589, Saudi ArabiaDepartment of Medical Laboratory Science, College of Applied Medical Sciences, University of Ha’il, Hail 55476, Saudi ArabiaDepartment of Medical Laboratory Science, College of Applied Medical Sciences, University of Ha’il, Hail 55476, Saudi ArabiaDepartment of Medical Laboratory Science, College of Applied Medical Sciences, University of Ha’il, Hail 55476, Saudi ArabiaSecurity Forces Hospital Program, Riyadh 11481, Saudi ArabiaInfections caused by multi-drug-resistant bacteria in patients with chronic diseases have been associated with high mortality and morbidity. While few reports have evaluated bacterial infections in multiple chronic disease patients, the focus of the current study was to investigate the prevalence of bacterial infections and the susceptibility profiles of causative strains among various groups of patients suffering from chronic diseases. Microbiological reports of patients suffering from cancer, diabetes mellitus, cardiovascular diseases, kidney diseases, and skin burns were retrospectively collected from a tertiary hospital in Saudi Arabia. Approximately 54.2% of recruited patients were males, and positive urine was the most prevalent specimen associated with kidney disease patients (25%)<i>. Escherichia coli</i> isolates were predominant among cardiovascular, kidney, and cancer patients. <i>Staphylococcus aureus</i> was commonly detected in diabetics and those with burns. Although resistance patterns varied based on the type of specimens and underlying diseases, <i>Escherichia coli</i> showed limited resistance to colistin, carbapenems, and tigecycline, while <i>S. aureus</i> demonstrated susceptibility to ciprofloxacin, gentamicin, and rifampin. These observations are crucial for clinicians and policymakers to ensure effective treatment plans and improve outcomes in these patients with comorbidity.https://www.mdpi.com/2076-2607/10/10/1907bacterial infectionschronic diseasesantibiotic-resistantdiabetes mellitus and skin burns |
| spellingShingle | Abdulrahman S. Bazaid Ahmed A. Punjabi Abdu Aldarhami Husam Qanash Ghaida Alsaif Hattan Gattan Heba Barnawi Bandar Alharbi Abdulaziz Alrashidi Abdulaziz Alqadi Bacterial Infections among Patients with Chronic Diseases at a Tertiary Care Hospital in Saudi Arabia Microorganisms bacterial infections chronic diseases antibiotic-resistant diabetes mellitus and skin burns |
| title | Bacterial Infections among Patients with Chronic Diseases at a Tertiary Care Hospital in Saudi Arabia |
| title_full | Bacterial Infections among Patients with Chronic Diseases at a Tertiary Care Hospital in Saudi Arabia |
| title_fullStr | Bacterial Infections among Patients with Chronic Diseases at a Tertiary Care Hospital in Saudi Arabia |
| title_full_unstemmed | Bacterial Infections among Patients with Chronic Diseases at a Tertiary Care Hospital in Saudi Arabia |
| title_short | Bacterial Infections among Patients with Chronic Diseases at a Tertiary Care Hospital in Saudi Arabia |
| title_sort | bacterial infections among patients with chronic diseases at a tertiary care hospital in saudi arabia |
| topic | bacterial infections chronic diseases antibiotic-resistant diabetes mellitus and skin burns |
| url | https://www.mdpi.com/2076-2607/10/10/1907 |
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