Optical coherence tomography angiography manifestations of different degrees of nonproliferative diabetic retinopathy
AIM: To investigate the differences in varying stages of non-proliferative diabetic retinopathy(NPDR)using optical coherence tomography angiography(OCTA).METHODS: Cross-sectional study. A total of 77 cases(77 eyes)of diabetic patients were included, and they were divided into non-diabetic retinopath...
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| Format: | Article |
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Press of International Journal of Ophthalmology (IJO PRESS)
2024-02-01
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| Series: | Guoji Yanke Zazhi |
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| Online Access: | http://ies.ijo.cn/cn_publish/2024/2/202402024.pdf |
| _version_ | 1797352749343440896 |
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| author | Dai Menghuan Li Dongli Cui Yixin Shen Lu Li Qirui Rao Lingna Guo Shurong Yuan Ling |
| author_facet | Dai Menghuan Li Dongli Cui Yixin Shen Lu Li Qirui Rao Lingna Guo Shurong Yuan Ling |
| author_sort | Dai Menghuan |
| collection | DOAJ |
| description | AIM: To investigate the differences in varying stages of non-proliferative diabetic retinopathy(NPDR)using optical coherence tomography angiography(OCTA).METHODS: Cross-sectional study. A total of 77 cases(77 eyes)of diabetic patients were included, and they were divided into non-diabetic retinopathy(NDR; 23 eyes)and non-proliferative diabetic retinopathy(NPDR; 54 eyes)groups, further subdivided into mild NPDR(20 eyes), moderate NPDR(20 eyes), and severe NPDR(14 eyes). Foveal avascular zone(FAZ)area, superficial and deep capillary plexus densities(SSP and DSP), and visual acuity(LogMAR)were compared between NDR and NPDR groups. Furthermore, the visual acuity, FAZ area and levels of SSP and DSP were compared in different degrees of NPDR. Correlation analysis were conducted to elucidate relationships between FAZ area, visual acuity, SSP, DSP, and severity of the disease.RESULTS: Compared with the NDR group, the visual acuity(LogMAR)and macular FAZ area increased, while SSP and DSP were decreased in the NPDR group(P<0.05); there were significant differences in visual acuity, FAZ area and SSP and DSP levels in different degrees of NPDR(P<0.05). Visual acuity(LogMAR)and FAZ area displayed a positive correlation with the severity of disease, while SSP and DSP showed a negative correlation.CONCLUSION: With the progression of NPDR, the visual acuity(LogMAR)and FAZ area increased, and the SSP and DSP decreased. |
| first_indexed | 2024-03-08T13:21:24Z |
| format | Article |
| id | doaj.art-25b1d7d4f3984f08a7588641b13696da |
| institution | Directory Open Access Journal |
| issn | 1672-5123 |
| language | English |
| last_indexed | 2024-03-08T13:21:24Z |
| publishDate | 2024-02-01 |
| publisher | Press of International Journal of Ophthalmology (IJO PRESS) |
| record_format | Article |
| series | Guoji Yanke Zazhi |
| spelling | doaj.art-25b1d7d4f3984f08a7588641b13696da2024-01-18T03:35:38ZengPress of International Journal of Ophthalmology (IJO PRESS)Guoji Yanke Zazhi1672-51232024-02-0124230731110.3980/j.issn.1672-5123.2024.2.24202402024Optical coherence tomography angiography manifestations of different degrees of nonproliferative diabetic retinopathyDai Menghuan0Li Dongli1Cui Yixin2Shen Lu3Li Qirui4Rao Lingna5Guo Shurong6Yuan Ling7Department of Ophthalmology, First Affiliated Hospital of Kunming Medical University, Kunming 650031, Yunnan Province, ChinaDepartment of Ophthalmology, First Affiliated Hospital of Kunming Medical University, Kunming 650031, Yunnan Province, ChinaDepartment of Ophthalmology, First Affiliated Hospital of Kunming Medical University, Kunming 650031, Yunnan Province, ChinaDepartment of Ophthalmology, First Affiliated Hospital of Kunming Medical University, Kunming 650031, Yunnan Province, ChinaDepartment of Ophthalmology, First Affiliated Hospital of Kunming Medical University, Kunming 650031, Yunnan Province, ChinaDepartment of Ophthalmology, First Affiliated Hospital of Kunming Medical University, Kunming 650031, Yunnan Province, ChinaDepartment of Ophthalmology, First Affiliated Hospital of Kunming Medical University, Kunming 650031, Yunnan Province, ChinaDepartment of Ophthalmology, First Affiliated Hospital of Kunming Medical University, Kunming 650031, Yunnan Province, ChinaAIM: To investigate the differences in varying stages of non-proliferative diabetic retinopathy(NPDR)using optical coherence tomography angiography(OCTA).METHODS: Cross-sectional study. A total of 77 cases(77 eyes)of diabetic patients were included, and they were divided into non-diabetic retinopathy(NDR; 23 eyes)and non-proliferative diabetic retinopathy(NPDR; 54 eyes)groups, further subdivided into mild NPDR(20 eyes), moderate NPDR(20 eyes), and severe NPDR(14 eyes). Foveal avascular zone(FAZ)area, superficial and deep capillary plexus densities(SSP and DSP), and visual acuity(LogMAR)were compared between NDR and NPDR groups. Furthermore, the visual acuity, FAZ area and levels of SSP and DSP were compared in different degrees of NPDR. Correlation analysis were conducted to elucidate relationships between FAZ area, visual acuity, SSP, DSP, and severity of the disease.RESULTS: Compared with the NDR group, the visual acuity(LogMAR)and macular FAZ area increased, while SSP and DSP were decreased in the NPDR group(P<0.05); there were significant differences in visual acuity, FAZ area and SSP and DSP levels in different degrees of NPDR(P<0.05). Visual acuity(LogMAR)and FAZ area displayed a positive correlation with the severity of disease, while SSP and DSP showed a negative correlation.CONCLUSION: With the progression of NPDR, the visual acuity(LogMAR)and FAZ area increased, and the SSP and DSP decreased.http://ies.ijo.cn/cn_publish/2024/2/202402024.pdfnon-proliferative diabetic retinopathyoptical coherence tomography angiography(octa)visual acuitymacular foveal avascular areasuperficial capillary plexusdeep capillary plexus |
| spellingShingle | Dai Menghuan Li Dongli Cui Yixin Shen Lu Li Qirui Rao Lingna Guo Shurong Yuan Ling Optical coherence tomography angiography manifestations of different degrees of nonproliferative diabetic retinopathy Guoji Yanke Zazhi non-proliferative diabetic retinopathy optical coherence tomography angiography(octa) visual acuity macular foveal avascular area superficial capillary plexus deep capillary plexus |
| title | Optical coherence tomography angiography manifestations of different degrees of nonproliferative diabetic retinopathy |
| title_full | Optical coherence tomography angiography manifestations of different degrees of nonproliferative diabetic retinopathy |
| title_fullStr | Optical coherence tomography angiography manifestations of different degrees of nonproliferative diabetic retinopathy |
| title_full_unstemmed | Optical coherence tomography angiography manifestations of different degrees of nonproliferative diabetic retinopathy |
| title_short | Optical coherence tomography angiography manifestations of different degrees of nonproliferative diabetic retinopathy |
| title_sort | optical coherence tomography angiography manifestations of different degrees of nonproliferative diabetic retinopathy |
| topic | non-proliferative diabetic retinopathy optical coherence tomography angiography(octa) visual acuity macular foveal avascular area superficial capillary plexus deep capillary plexus |
| url | http://ies.ijo.cn/cn_publish/2024/2/202402024.pdf |
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