Transcriptional networks specifying homeostatic and inflammatory programs of gene expression in human aortic endothelial cells

Transcriptional networks specifying homeostatic and inflammatory programs of gene expression in human aortic endothelial cells

Endothelial cells (ECs) are critical determinants of vascular homeostasis and inflammation, but transcriptional mechanisms specifying their identities and functional states remain poorly understood. Here, we report a genome-wide assessment of regulatory landscapes of primary human aortic endothelial...

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Bibliographic Details
Main Authors: Nicholas T Hogan, Michael B Whalen, Lindsey K Stolze, Nizar K Hadeli, Michael T Lam, James R Springstead, Christopher K Glass, Casey E Romanoski
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2017-06-01
Series:eLife
Subjects:
endothelial cell
enhancers
inflammation
cardiovascular disease
atherosclerosis
Online Access:https://elifesciences.org/articles/22536

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