Enteroparasitosis prevalence and parasitism influence in clinical outcomes of tuberculosis patients with or without HIV co-infection in a reference hospital in Rio de Janeiro (2000-2006)
Tuberculosis and intestinal parasites affect primarily low social and economic level populations, living clustered in precarious habitational settings. One of the interesting aspects of this interaction is the parasitism influence in cellular response to tuberculosis. In the present study, we evalua...
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| Format: | Article |
| Language: | English |
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Elsevier
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| Series: | Brazilian Journal of Infectious Diseases |
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| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702009000600008&lng=en&tlng=en |
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| author | Luanda M.S. Neto Raquel de Vasconcellos Carvalhaes de Oliveira Paulo Renato Totino Flavia Marinho Sant'Anna Viviane de Oliveira Coelho Valeria Cavalcanti Rolla Graziela M. Zanini |
| author_facet | Luanda M.S. Neto Raquel de Vasconcellos Carvalhaes de Oliveira Paulo Renato Totino Flavia Marinho Sant'Anna Viviane de Oliveira Coelho Valeria Cavalcanti Rolla Graziela M. Zanini |
| author_sort | Luanda M.S. Neto |
| collection | DOAJ |
| description | Tuberculosis and intestinal parasites affect primarily low social and economic level populations, living clustered in precarious habitational settings. One of the interesting aspects of this interaction is the parasitism influence in cellular response to tuberculosis. In the present study, we evaluated the prevalence of enteroparasitosis in tuberculosis patients, HIV-infected and non HIV infected, and we observed the influence of helminth presence in the response to tuberculin skin test (TST) and tuberculosis clinical outcomes. From 607 clinical records reviewed, 327 individuals met the study inclusion criteria and did not present any exclusion criteria. The prevalence of enteroparasites observed was 19.6%. There was no significant association among TST result and the variables related to the presence of: helminthes, protozoa, and stool test for parasites result (p>0.5). Considering the survival of this cohort, we may observe that there is no significant difference (p>0.05) between the survival curves of parasited and non parasited individuals. Solely the variable "eosinophils" presents a statistically significant association (p<0.001) with helminthes, all other associations are considered not significant. Our findings neither show an association between helminthic infection and a favorable tuberculosis outcome, nor between parasitism and TST response, unlike other in vitro studies. Apparently, experimental data do not correspond to the clinical findings. |
| first_indexed | 2024-04-13T03:34:37Z |
| format | Article |
| id | doaj.art-25b68cdf10394e708230a27db8df4998 |
| institution | Directory Open Access Journal |
| issn | 1678-4391 |
| language | English |
| last_indexed | 2024-04-13T03:34:37Z |
| publisher | Elsevier |
| record_format | Article |
| series | Brazilian Journal of Infectious Diseases |
| spelling | doaj.art-25b68cdf10394e708230a27db8df49982022-12-22T03:04:21ZengElsevierBrazilian Journal of Infectious Diseases1678-439113642743210.1590/S1413-86702009000600008S1413-86702009000600008Enteroparasitosis prevalence and parasitism influence in clinical outcomes of tuberculosis patients with or without HIV co-infection in a reference hospital in Rio de Janeiro (2000-2006)Luanda M.S. Neto0Raquel de Vasconcellos Carvalhaes de Oliveira1Paulo Renato Totino2Flavia Marinho Sant'Anna3Viviane de Oliveira Coelho4Valeria Cavalcanti Rolla5Graziela M. Zanini6Fundação Oswaldo CruzFundação Oswaldo CruzFundação Oswaldo CruzFundação Oswaldo CruzFundação Oswaldo CruzFundação Oswaldo CruzFundação Oswaldo CruzTuberculosis and intestinal parasites affect primarily low social and economic level populations, living clustered in precarious habitational settings. One of the interesting aspects of this interaction is the parasitism influence in cellular response to tuberculosis. In the present study, we evaluated the prevalence of enteroparasitosis in tuberculosis patients, HIV-infected and non HIV infected, and we observed the influence of helminth presence in the response to tuberculin skin test (TST) and tuberculosis clinical outcomes. From 607 clinical records reviewed, 327 individuals met the study inclusion criteria and did not present any exclusion criteria. The prevalence of enteroparasites observed was 19.6%. There was no significant association among TST result and the variables related to the presence of: helminthes, protozoa, and stool test for parasites result (p>0.5). Considering the survival of this cohort, we may observe that there is no significant difference (p>0.05) between the survival curves of parasited and non parasited individuals. Solely the variable "eosinophils" presents a statistically significant association (p<0.001) with helminthes, all other associations are considered not significant. Our findings neither show an association between helminthic infection and a favorable tuberculosis outcome, nor between parasitism and TST response, unlike other in vitro studies. Apparently, experimental data do not correspond to the clinical findings.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702009000600008&lng=en&tlng=enTuberculosisintestinal parasitestuberculin skin testsurvival |
| spellingShingle | Luanda M.S. Neto Raquel de Vasconcellos Carvalhaes de Oliveira Paulo Renato Totino Flavia Marinho Sant'Anna Viviane de Oliveira Coelho Valeria Cavalcanti Rolla Graziela M. Zanini Enteroparasitosis prevalence and parasitism influence in clinical outcomes of tuberculosis patients with or without HIV co-infection in a reference hospital in Rio de Janeiro (2000-2006) Brazilian Journal of Infectious Diseases Tuberculosis intestinal parasites tuberculin skin test survival |
| title | Enteroparasitosis prevalence and parasitism influence in clinical outcomes of tuberculosis patients with or without HIV co-infection in a reference hospital in Rio de Janeiro (2000-2006) |
| title_full | Enteroparasitosis prevalence and parasitism influence in clinical outcomes of tuberculosis patients with or without HIV co-infection in a reference hospital in Rio de Janeiro (2000-2006) |
| title_fullStr | Enteroparasitosis prevalence and parasitism influence in clinical outcomes of tuberculosis patients with or without HIV co-infection in a reference hospital in Rio de Janeiro (2000-2006) |
| title_full_unstemmed | Enteroparasitosis prevalence and parasitism influence in clinical outcomes of tuberculosis patients with or without HIV co-infection in a reference hospital in Rio de Janeiro (2000-2006) |
| title_short | Enteroparasitosis prevalence and parasitism influence in clinical outcomes of tuberculosis patients with or without HIV co-infection in a reference hospital in Rio de Janeiro (2000-2006) |
| title_sort | enteroparasitosis prevalence and parasitism influence in clinical outcomes of tuberculosis patients with or without hiv co infection in a reference hospital in rio de janeiro 2000 2006 |
| topic | Tuberculosis intestinal parasites tuberculin skin test survival |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702009000600008&lng=en&tlng=en |
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