Outer Membrane Protein A Conservation among Orientia tsutsugamushi Isolates Suggests Its Potential as a Protective Antigen and Diagnostic Target

Outer Membrane Protein A Conservation among Orientia tsutsugamushi Isolates Suggests Its Potential as a Protective Antigen and Diagnostic Target

Scrub typhus threatens one billion people in the Asia-Pacific area and cases have emerged outside this region. It is caused by infection with any of the multitude of strains of the bacterium Orientia tsutsugamushi. A vaccine that affords heterologous protection and a commercially-available molecular...

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Bibliographic Details
Main Authors: Sean M. Evans, Haley E. Adcox, Lauren VieBrock, Ryan S. Green, Alison Luce-Fedrow, Suschsmita Chattopadhyay, Ju Jiang, Richard T. Marconi, Daniel Paris, Allen L. Richards, Jason A. Carlyon
Format: Article
Language:English
Published: MDPI AG 2018-06-01
Series:Tropical Medicine and Infectious Disease
Subjects:
scrub typhus
Orientia tsutsugamushi
Rickettsia
Rickettsiales
outer membrane protein A
Anaplasma
Online Access:http://www.mdpi.com/2414-6366/3/2/63

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