Investigation of Cuprizone-Induced Demyelination in mGFAP-Driven Conditional Transient Receptor Potential Ankyrin 1 (TRPA1) Receptor Knockout Mice

Investigation of Cuprizone-Induced Demyelination in mGFAP-Driven Conditional Transient Receptor Potential Ankyrin 1 (TRPA1) Receptor Knockout Mice

Transient receptor potential ankyrin 1 (TRPA1) receptors are non-selective cation channels responsive to a variety of exogenous irritants and endogenous stimuli including products of oxidative stress. It is mainly expressed by primary sensory neurons; however, expression of TRPA1 by astrocytes and o...

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Bibliographic Details
Main Authors: Gábor Kriszta, Balázs Nemes, Zoltán Sándor, Péter Ács, Sámuel Komoly, Zoltán Berente, Kata Bölcskei, Erika Pintér
Format: Article
Language:English
Published: MDPI AG 2019-12-01
Series:Cells
Subjects:
transient receptor potential ankyrin 1
cuprizone
demyelination
astrocyte
conditional knockout
magnetic resonance imaging
Online Access:https://www.mdpi.com/2073-4409/9/1/81

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