Human Coronavirus NL63, France
The human coronavirus NL63 (HCoV-NL63) was first identified in the Netherlands, and its circulation in France has not been investigated. We studied HCoV-NL63 infection in hospitalized children diagnosed with respiratory tract infections. From November 2002 to April 2003, we evaluated 300 respiratory...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Centers for Disease Control and Prevention
2005-08-01
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| Series: | Emerging Infectious Diseases |
| Subjects: | |
| Online Access: | https://wwwnc.cdc.gov/eid/article/11/8/05-0110_article |
| _version_ | 1819109489669832704 |
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| author | Astrid Vabret Thomas Mourez Julia Dina Lia van der Hoek Stéphanie Gouarin Joëlle Petitjean Jacques Brouard François Freymuth |
| author_facet | Astrid Vabret Thomas Mourez Julia Dina Lia van der Hoek Stéphanie Gouarin Joëlle Petitjean Jacques Brouard François Freymuth |
| author_sort | Astrid Vabret |
| collection | DOAJ |
| description | The human coronavirus NL63 (HCoV-NL63) was first identified in the Netherlands, and its circulation in France has not been investigated. We studied HCoV-NL63 infection in hospitalized children diagnosed with respiratory tract infections. From November 2002 to April 2003, we evaluated 300 respiratory specimens for HCoV-NL63. Of the 300 samples, 28 (9.3%) were positive for HCoV-NL63. The highest prevalence was found in February (18%). The main symptoms were fever (61%), rhinitis (39%), bronchiolitis (39%), digestive problems (33%), otitis (28%), pharyngitis (22%), and conjunctivitis (17%). A fragment of the spike protein gene was sequenced to determine the variety of circulating HCoV-NL63. Phylogenetic analysis indicated that strains with different genetic markers cocirculate in France. |
| first_indexed | 2024-12-22T03:26:39Z |
| format | Article |
| id | doaj.art-25c17a6d7ab0434dba94bdc99cd85e03 |
| institution | Directory Open Access Journal |
| issn | 1080-6040 1080-6059 |
| language | English |
| last_indexed | 2024-12-22T03:26:39Z |
| publishDate | 2005-08-01 |
| publisher | Centers for Disease Control and Prevention |
| record_format | Article |
| series | Emerging Infectious Diseases |
| spelling | doaj.art-25c17a6d7ab0434dba94bdc99cd85e032022-12-21T18:40:35ZengCenters for Disease Control and PreventionEmerging Infectious Diseases1080-60401080-60592005-08-011181225122910.3201/eid1108.050110Human Coronavirus NL63, FranceAstrid VabretThomas MourezJulia DinaLia van der HoekStéphanie GouarinJoëlle PetitjeanJacques BrouardFrançois FreymuthThe human coronavirus NL63 (HCoV-NL63) was first identified in the Netherlands, and its circulation in France has not been investigated. We studied HCoV-NL63 infection in hospitalized children diagnosed with respiratory tract infections. From November 2002 to April 2003, we evaluated 300 respiratory specimens for HCoV-NL63. Of the 300 samples, 28 (9.3%) were positive for HCoV-NL63. The highest prevalence was found in February (18%). The main symptoms were fever (61%), rhinitis (39%), bronchiolitis (39%), digestive problems (33%), otitis (28%), pharyngitis (22%), and conjunctivitis (17%). A fragment of the spike protein gene was sequenced to determine the variety of circulating HCoV-NL63. Phylogenetic analysis indicated that strains with different genetic markers cocirculate in France.https://wwwnc.cdc.gov/eid/article/11/8/05-0110_articleKeywords: phylogenetic analysiscoronavirus NL63molecular detectionpneumoniabronchiolitismultiplex assay |
| spellingShingle | Astrid Vabret Thomas Mourez Julia Dina Lia van der Hoek Stéphanie Gouarin Joëlle Petitjean Jacques Brouard François Freymuth Human Coronavirus NL63, France Emerging Infectious Diseases Keywords: phylogenetic analysis coronavirus NL63 molecular detection pneumonia bronchiolitis multiplex assay |
| title | Human Coronavirus NL63, France |
| title_full | Human Coronavirus NL63, France |
| title_fullStr | Human Coronavirus NL63, France |
| title_full_unstemmed | Human Coronavirus NL63, France |
| title_short | Human Coronavirus NL63, France |
| title_sort | human coronavirus nl63 france |
| topic | Keywords: phylogenetic analysis coronavirus NL63 molecular detection pneumonia bronchiolitis multiplex assay |
| url | https://wwwnc.cdc.gov/eid/article/11/8/05-0110_article |
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