MitoQ protects against high glucose-induced brain microvascular endothelial cells injury via the Nrf2/HO-1 pathway

MitoQ protects against high glucose-induced brain microvascular endothelial cells injury via the Nrf2/HO-1 pathway

Brain microvascular endothelial cells (BMECs) dysfunction is related to the pathogenesis of neurovascular complication of diabetes mellitus that adversely lead to various CNS disorders. Mitoquinone (MitoQ) is a mitochondria targeted antioxidant that exerts multiple protective effects in many oxidati...

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Bibliographic Details
Main Authors:	Min-yan Yang, Zhen Fan, Zhao Zhang, Jin Fan
Format:	Article
Language:	English
Published:	Elsevier 2021-01-01
Series:	Journal of Pharmacological Sciences
Subjects:	MitoQ Nrf2 Mitochondrial ROS Brain microvascular endothelial cells Diabetes
Online Access:	http://www.sciencedirect.com/science/article/pii/S1347861320301055

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