The Anticancer Effect of a Flavonoid-Rich Extract of Bergamot Juice in THP-1 Cells Engages the SIRT2/AKT/p53 Pathway
Novel targets are constantly sought to fight hematologic malignancies. In this regard, high levels of SIRT2 expression are associated with unfavorable prognosis of acute myeloid leukemia. The interest in the plant kingdom has allowed the identification of ever-new anti-leukemic agents. <i>Citr...
Main Authors: | Alessandro Maugeri, Caterina Russo, Laura Musumeci, Giovanni Enrico Lombardo, Giovambattista De Sarro, Davide Barreca, Santa Cirmi, Michele Navarra |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2022-10-01
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Series: | Pharmaceutics |
Subjects: | |
Online Access: | https://www.mdpi.com/1999-4923/14/10/2168 |
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