The Role of P53 in Oral Cancer - A Review

The Role of P53 in Oral Cancer - A Review

P53 is a nuclear phosphoprotein encoded by the tumor suppressor gene p53. This P53 protein plays an important role in the regulation of normal cell proliferation by causing cell cycle arrest. Mutation of p53 gene produces an altered P53 protein leading to loss of cell cycle control. As a result, the...

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Bibliographic Details
Main Authors: C Poornima, P G Agnihotri, S Y Rajan, B N Padmavathi, R Guruprasad
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2005-01-01
Series:Journal of Indian Academy of Oral Medicine and Radiology
Subjects:
Tumor suppressor gene
p53 gene
P53 protein
Cell cycle arrest
Apoptosis
Online Access:http://www.jiaomr.in/article.asp?issn=0972-1363;year=2005;volume=17;issue=4;spage=153;epage=156;aulast=Poornima;type=0

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