Relevance of Cell-ECM Interactions: From a Biological Perspective to the Mathematical Modeling
Cell migration across fibre networks and micro-channel structures has been widely demonstrated to be strongly influenced by the interactions between moving individuals and the surrounding extracellular matrix as well as by the mechanical properties of cell nucleus. In this respect, our work will be...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
EDP Sciences
2015-01-01
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| Series: | ITM Web of Conferences |
| Online Access: | http://dx.doi.org/10.1051/itmconf/20150500004 |
| _version_ | 1819179754513760256 |
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| author | Preziosi Luigi Scianna Marco |
| author_facet | Preziosi Luigi Scianna Marco |
| author_sort | Preziosi Luigi |
| collection | DOAJ |
| description | Cell migration across fibre networks and micro-channel structures has been widely demonstrated to be strongly influenced by the interactions between moving individuals and the surrounding extracellular matrix as well as by the mechanical properties of cell nucleus. In this respect, our work will be devoted to describe several mathematical models, which deal either with cell adhesion mechanics or with suitable analysis of the role played in cell movement by nucleus stiffness. In particular, the presented approaches span from discrete individual-based methods to continuous models and provide useful insights into selected determinant underlying cell migration within two-and three-dimensional matrix environments. |
| first_indexed | 2024-12-22T22:03:28Z |
| format | Article |
| id | doaj.art-25ccef18ba6844afb72b9dfa7ea39cd1 |
| institution | Directory Open Access Journal |
| issn | 2271-2097 |
| language | English |
| last_indexed | 2024-12-22T22:03:28Z |
| publishDate | 2015-01-01 |
| publisher | EDP Sciences |
| record_format | Article |
| series | ITM Web of Conferences |
| spelling | doaj.art-25ccef18ba6844afb72b9dfa7ea39cd12022-12-21T18:11:03ZengEDP SciencesITM Web of Conferences2271-20972015-01-0150000410.1051/itmconf/20150500004itmconf_mod2015_00004Relevance of Cell-ECM Interactions: From a Biological Perspective to the Mathematical ModelingPreziosi Luigi0Scianna Marco1Dipartimento di Scienze Matematiche, Politecnico di TorinoDipartimento di Scienze Matematiche, Politecnico di TorinoCell migration across fibre networks and micro-channel structures has been widely demonstrated to be strongly influenced by the interactions between moving individuals and the surrounding extracellular matrix as well as by the mechanical properties of cell nucleus. In this respect, our work will be devoted to describe several mathematical models, which deal either with cell adhesion mechanics or with suitable analysis of the role played in cell movement by nucleus stiffness. In particular, the presented approaches span from discrete individual-based methods to continuous models and provide useful insights into selected determinant underlying cell migration within two-and three-dimensional matrix environments.http://dx.doi.org/10.1051/itmconf/20150500004 |
| spellingShingle | Preziosi Luigi Scianna Marco Relevance of Cell-ECM Interactions: From a Biological Perspective to the Mathematical Modeling ITM Web of Conferences |
| title | Relevance of Cell-ECM Interactions: From a Biological Perspective to the Mathematical Modeling |
| title_full | Relevance of Cell-ECM Interactions: From a Biological Perspective to the Mathematical Modeling |
| title_fullStr | Relevance of Cell-ECM Interactions: From a Biological Perspective to the Mathematical Modeling |
| title_full_unstemmed | Relevance of Cell-ECM Interactions: From a Biological Perspective to the Mathematical Modeling |
| title_short | Relevance of Cell-ECM Interactions: From a Biological Perspective to the Mathematical Modeling |
| title_sort | relevance of cell ecm interactions from a biological perspective to the mathematical modeling |
| url | http://dx.doi.org/10.1051/itmconf/20150500004 |
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