3D,2D-QSAR study and docking of novel quinazolines as potential target drugs for osteosarcoma

3D,2D-QSAR study and docking of novel quinazolines as potential target drugs for osteosarcoma

Background: Quinazolines are an important class of benzopyrimidine heterocyclic compounds with a promising antitumor activity that can be used for the design and development of osteosarcoma target compounds.Objective: To predict the compound activity of quinazoline compounds by constructing 2D- and...

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Bibliographic Details
Main Authors:	Zheng Lian, Chenglin Sang, Nianhu Li, Honglin Zhai, Wenzhe Bai
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-02-01
Series:	Frontiers in Pharmacology
Subjects:	quinazolines structure-activity relationship osteosarcoma Targeted drugs small molecule docking
Online Access:	https://www.frontiersin.org/articles/10.3389/fphar.2023.1124895/full

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