Endothelin Receptor Antagonists in Kidney Disease

Endothelin (ET) is found to be increased in kidney disease secondary to hyperglycaemia, hypertension, acidosis, and the presence of insulin or proinflammatory cytokines. In this context, ET, via the endothelin receptor type A (ET<sub>A</sub>) activation, causes sustained vasoconstriction...

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Bibliographic Details
Main Authors: Irene Martínez-Díaz, Nerea Martos, Carmen Llorens-Cebrià, Francisco J. Álvarez, Patricia W. Bedard, Ander Vergara, Conxita Jacobs-Cachá, Maria José Soler
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/24/4/3427

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