Corneal Analysis with Swept Source Optical Coherence Tomography in Patients with Coexisting Cataract and Fuchs Endothelial Corneal Dystrophy
This study focused on defining the characteristic features of keratometry and pachymetry elevation maps based on swept source optical coherence tomography (SS OCT) in Fuchs endothelial corneal dystrophy (FECD) eyes with a coexisting cataract. 70 eyes of 35 patients diagnosed with FECD and a coexisti...
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MDPI AG
2021-02-01
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| Series: | Diagnostics |
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| Online Access: | https://www.mdpi.com/2075-4418/11/2/223 |
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| author | Anna Nowińska Edyta Chlasta-Twardzik Michał Dembski Klaudia Ulfik-Dembska Edward Wylęgała |
| author_facet | Anna Nowińska Edyta Chlasta-Twardzik Michał Dembski Klaudia Ulfik-Dembska Edward Wylęgała |
| author_sort | Anna Nowińska |
| collection | DOAJ |
| description | This study focused on defining the characteristic features of keratometry and pachymetry elevation maps based on swept source optical coherence tomography (SS OCT) in Fuchs endothelial corneal dystrophy (FECD) eyes with a coexisting cataract. 70 eyes of 35 patients diagnosed with FECD and a coexisting cataract and 70 control eyes were included in this prospective, controlled, observational, cross-sectional study. Features characteristic of intermediately affected eyes included an increased corneal thinnest thickness (CTT) (<i>p</i> = 0.01), 3 and 6 mm asymmetry (<i>p</i> < 0.0001), higher order Fourier indices (<i>p</i> < 0.05 and <i>p</i> ≤ 0.0001, respectively), chord µ, and a posterior Ectasia Screening Index (pESI) (<i>p</i> < 0.01). The lack of agreement between the anterior and posterior elevation map and a significant area of negative values in the posterior map were detected. In advanced FECD eyes, our study additionally revealed decreased posterior keratometry steep (Ks), keratometry flat (Kf), keratometry average (AvgK), eccentricity (Ecc), an increased corneal apex thickness (CAT), and decreased 3 and 6 mm posterior spherical indices (<i>p</i> < 0.0001 for all of the above). Characteristic features of subclinical FECD, independent of the corneal thickness, can be detected by SS OCT and should be considered during the preoperative assessment of patients with a coexisting cataract. |
| first_indexed | 2024-03-09T06:02:01Z |
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| institution | Directory Open Access Journal |
| issn | 2075-4418 |
| language | English |
| last_indexed | 2024-03-09T06:02:01Z |
| publishDate | 2021-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Diagnostics |
| spelling | doaj.art-25d2dff3845b48ed8f4d7b54e64d2aae2023-12-03T12:07:31ZengMDPI AGDiagnostics2075-44182021-02-0111222310.3390/diagnostics11020223Corneal Analysis with Swept Source Optical Coherence Tomography in Patients with Coexisting Cataract and Fuchs Endothelial Corneal DystrophyAnna Nowińska0Edyta Chlasta-Twardzik1Michał Dembski2Klaudia Ulfik-Dembska3Edward Wylęgała4Chair and Clinical Department of Ophthalmology, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, 40-055 Katowice, PolandChair and Clinical Department of Ophthalmology, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, 40-055 Katowice, PolandChair and Clinical Department of Ophthalmology, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, 40-055 Katowice, PolandChair and Clinical Department of Ophthalmology, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, 40-055 Katowice, PolandChair and Clinical Department of Ophthalmology, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, 40-055 Katowice, PolandThis study focused on defining the characteristic features of keratometry and pachymetry elevation maps based on swept source optical coherence tomography (SS OCT) in Fuchs endothelial corneal dystrophy (FECD) eyes with a coexisting cataract. 70 eyes of 35 patients diagnosed with FECD and a coexisting cataract and 70 control eyes were included in this prospective, controlled, observational, cross-sectional study. Features characteristic of intermediately affected eyes included an increased corneal thinnest thickness (CTT) (<i>p</i> = 0.01), 3 and 6 mm asymmetry (<i>p</i> < 0.0001), higher order Fourier indices (<i>p</i> < 0.05 and <i>p</i> ≤ 0.0001, respectively), chord µ, and a posterior Ectasia Screening Index (pESI) (<i>p</i> < 0.01). The lack of agreement between the anterior and posterior elevation map and a significant area of negative values in the posterior map were detected. In advanced FECD eyes, our study additionally revealed decreased posterior keratometry steep (Ks), keratometry flat (Kf), keratometry average (AvgK), eccentricity (Ecc), an increased corneal apex thickness (CAT), and decreased 3 and 6 mm posterior spherical indices (<i>p</i> < 0.0001 for all of the above). Characteristic features of subclinical FECD, independent of the corneal thickness, can be detected by SS OCT and should be considered during the preoperative assessment of patients with a coexisting cataract.https://www.mdpi.com/2075-4418/11/2/223fuchs endothelial corneal dystrophyoptical coherence tomographycataractcorneal parameters |
| spellingShingle | Anna Nowińska Edyta Chlasta-Twardzik Michał Dembski Klaudia Ulfik-Dembska Edward Wylęgała Corneal Analysis with Swept Source Optical Coherence Tomography in Patients with Coexisting Cataract and Fuchs Endothelial Corneal Dystrophy Diagnostics fuchs endothelial corneal dystrophy optical coherence tomography cataract corneal parameters |
| title | Corneal Analysis with Swept Source Optical Coherence Tomography in Patients with Coexisting Cataract and Fuchs Endothelial Corneal Dystrophy |
| title_full | Corneal Analysis with Swept Source Optical Coherence Tomography in Patients with Coexisting Cataract and Fuchs Endothelial Corneal Dystrophy |
| title_fullStr | Corneal Analysis with Swept Source Optical Coherence Tomography in Patients with Coexisting Cataract and Fuchs Endothelial Corneal Dystrophy |
| title_full_unstemmed | Corneal Analysis with Swept Source Optical Coherence Tomography in Patients with Coexisting Cataract and Fuchs Endothelial Corneal Dystrophy |
| title_short | Corneal Analysis with Swept Source Optical Coherence Tomography in Patients with Coexisting Cataract and Fuchs Endothelial Corneal Dystrophy |
| title_sort | corneal analysis with swept source optical coherence tomography in patients with coexisting cataract and fuchs endothelial corneal dystrophy |
| topic | fuchs endothelial corneal dystrophy optical coherence tomography cataract corneal parameters |
| url | https://www.mdpi.com/2075-4418/11/2/223 |
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