The Importance of Intra-Islet Communication in the Function and Plasticity of the Islets of Langerhans during Health and Diabetes

The Importance of Intra-Islet Communication in the Function and Plasticity of the Islets of Langerhans during Health and Diabetes

Islets of Langerhans are anatomically dispersed within the pancreas and exhibit regulatory coordination between islets in response to nutritional and inflammatory stimuli. However, within individual islets, there is also multi-faceted coordination of function between individual beta-cells, and betwe...

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Bibliographic Details
Main Authors: Thomas G. Hill, David J. Hill
Format: Article
Language:English
Published: MDPI AG 2024-04-01
Series:International Journal of Molecular Sciences
Subjects:
islets of Langerhans
beta-cell
paracrine
plasticity
type 1 diabetes
type 2 diabetes
Online Access:https://www.mdpi.com/1422-0067/25/7/4070

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