Intention to use PrEP among men who have sex with men and engage in chemsex: an international descriptive study
Background: Pre-exposure prophylaxis (PrEP) is a valuable tool in the response to the HIV epidemic, recommended for groups with a higher risk of HIV infection, such as men who have sex with men (MSM), particularly in the context of high-risk sexual behavior such as chemsex. Purpose: This study aimed...
| Main Authors: | , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2023-10-01
|
| Series: | Therapeutic Advances in Infectious Disease |
| Online Access: | https://doi.org/10.1177/20499361231206918 |
| _version_ | 1797647942926991360 |
|---|---|
| author | Álvaro Francisco Lopes de Sousa Caíque Jordan Nunes Ribeiro Guilherme Reis de Santana Santos Layze Braz de Oliveira Emerson Lucas Silva Camargo Shirley Verônica Melo Almeida Lima Inara Viviane de Oliveira Sena Márcio Bezerra-Santos Odinéa Maria Amorim Batista Anderson Reis de Sousa Isabel Amélia Costa Mendes |
| author_facet | Álvaro Francisco Lopes de Sousa Caíque Jordan Nunes Ribeiro Guilherme Reis de Santana Santos Layze Braz de Oliveira Emerson Lucas Silva Camargo Shirley Verônica Melo Almeida Lima Inara Viviane de Oliveira Sena Márcio Bezerra-Santos Odinéa Maria Amorim Batista Anderson Reis de Sousa Isabel Amélia Costa Mendes |
| author_sort | Álvaro Francisco Lopes de Sousa |
| collection | DOAJ |
| description | Background: Pre-exposure prophylaxis (PrEP) is a valuable tool in the response to the HIV epidemic, recommended for groups with a higher risk of HIV infection, such as men who have sex with men (MSM), particularly in the context of high-risk sexual behavior such as chemsex. Purpose: This study aimed to analyze the prevalence and factors associated with the intention to use PrEP among MSM who engage in chemsex in Brazil and Portugal. Methods: This was a cross-sectional study of a secondary dataset from a larger study conducted between January 2020 and May 2021 throughout Brazil and Portugal involving 1852 MSM who engage in chemsex. An initial descriptive analysis was performed to calculate the absolute and relative frequencies of independent variables related to the intention to use PrEP among MSM. A multivariate regression model was developed to identify factors independently associated with the intention to use PrEP. Results: Although a high level of PrEP knowledge (85.75%) was observed among MSM who engage in chemsex, the prevalence of intention to use PrEP was only 59.07%. Five variables were associated with a higher prevalence of intention to use PrEP [engaging in double penetration – adjusted prevalence ratio (aPR): 1.56, 95% CI: 1.44–1.69; being assigned female sex at birth – aPR: 1.34, 95% CI: 1.12–1.61; cruising – aPR: 1.21, 95% CI: 1.06–1.38; not using condoms – aPR: 1.20, 95% CI: 1.05–1.36; and being an immigrant – aPR: 1.16; 95% CI: 1.07–1.25], while having knowledge of postexposure prophylaxis (aPR: 0.91; 95% CI: 0.84–0.98), having a casual sexual partner (aPR: 0.86 and 0.85; 95% CI: 0.74–0.99 and 0.74–0.98), and engaging in group sex (aPR: 0.81; 95% CI: 0.73–0.90) were associated with a lower intention to use PrEP. Conclusion: The intention to use PrEP among MSM who engage in chemsex was high, and several factors were associated with this intention. Understanding the factors associated with the intention to use PrEP among MSM practicing chemsex is crucial for developing targeted interventions to increase PrEP uptake in this population. The results of this study suggest that tailored approaches are necessary to promote PrEP use in this population. |
| first_indexed | 2024-03-11T15:24:56Z |
| format | Article |
| id | doaj.art-25d6153466464904b70d7030ae8932b2 |
| institution | Directory Open Access Journal |
| issn | 2049-937X |
| language | English |
| last_indexed | 2024-03-11T15:24:56Z |
| publishDate | 2023-10-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Therapeutic Advances in Infectious Disease |
| spelling | doaj.art-25d6153466464904b70d7030ae8932b22023-10-27T21:03:30ZengSAGE PublishingTherapeutic Advances in Infectious Disease2049-937X2023-10-011010.1177/20499361231206918Intention to use PrEP among men who have sex with men and engage in chemsex: an international descriptive studyÁlvaro Francisco Lopes de SousaCaíque Jordan Nunes RibeiroGuilherme Reis de Santana SantosLayze Braz de OliveiraEmerson Lucas Silva CamargoShirley Verônica Melo Almeida LimaInara Viviane de Oliveira SenaMárcio Bezerra-SantosOdinéa Maria Amorim BatistaAnderson Reis de SousaIsabel Amélia Costa MendesBackground: Pre-exposure prophylaxis (PrEP) is a valuable tool in the response to the HIV epidemic, recommended for groups with a higher risk of HIV infection, such as men who have sex with men (MSM), particularly in the context of high-risk sexual behavior such as chemsex. Purpose: This study aimed to analyze the prevalence and factors associated with the intention to use PrEP among MSM who engage in chemsex in Brazil and Portugal. Methods: This was a cross-sectional study of a secondary dataset from a larger study conducted between January 2020 and May 2021 throughout Brazil and Portugal involving 1852 MSM who engage in chemsex. An initial descriptive analysis was performed to calculate the absolute and relative frequencies of independent variables related to the intention to use PrEP among MSM. A multivariate regression model was developed to identify factors independently associated with the intention to use PrEP. Results: Although a high level of PrEP knowledge (85.75%) was observed among MSM who engage in chemsex, the prevalence of intention to use PrEP was only 59.07%. Five variables were associated with a higher prevalence of intention to use PrEP [engaging in double penetration – adjusted prevalence ratio (aPR): 1.56, 95% CI: 1.44–1.69; being assigned female sex at birth – aPR: 1.34, 95% CI: 1.12–1.61; cruising – aPR: 1.21, 95% CI: 1.06–1.38; not using condoms – aPR: 1.20, 95% CI: 1.05–1.36; and being an immigrant – aPR: 1.16; 95% CI: 1.07–1.25], while having knowledge of postexposure prophylaxis (aPR: 0.91; 95% CI: 0.84–0.98), having a casual sexual partner (aPR: 0.86 and 0.85; 95% CI: 0.74–0.99 and 0.74–0.98), and engaging in group sex (aPR: 0.81; 95% CI: 0.73–0.90) were associated with a lower intention to use PrEP. Conclusion: The intention to use PrEP among MSM who engage in chemsex was high, and several factors were associated with this intention. Understanding the factors associated with the intention to use PrEP among MSM practicing chemsex is crucial for developing targeted interventions to increase PrEP uptake in this population. The results of this study suggest that tailored approaches are necessary to promote PrEP use in this population.https://doi.org/10.1177/20499361231206918 |
| spellingShingle | Álvaro Francisco Lopes de Sousa Caíque Jordan Nunes Ribeiro Guilherme Reis de Santana Santos Layze Braz de Oliveira Emerson Lucas Silva Camargo Shirley Verônica Melo Almeida Lima Inara Viviane de Oliveira Sena Márcio Bezerra-Santos Odinéa Maria Amorim Batista Anderson Reis de Sousa Isabel Amélia Costa Mendes Intention to use PrEP among men who have sex with men and engage in chemsex: an international descriptive study Therapeutic Advances in Infectious Disease |
| title | Intention to use PrEP among men who have sex with men and engage in chemsex: an international descriptive study |
| title_full | Intention to use PrEP among men who have sex with men and engage in chemsex: an international descriptive study |
| title_fullStr | Intention to use PrEP among men who have sex with men and engage in chemsex: an international descriptive study |
| title_full_unstemmed | Intention to use PrEP among men who have sex with men and engage in chemsex: an international descriptive study |
| title_short | Intention to use PrEP among men who have sex with men and engage in chemsex: an international descriptive study |
| title_sort | intention to use prep among men who have sex with men and engage in chemsex an international descriptive study |
| url | https://doi.org/10.1177/20499361231206918 |
| work_keys_str_mv | AT alvarofranciscolopesdesousa intentiontouseprepamongmenwhohavesexwithmenandengageinchemsexaninternationaldescriptivestudy AT caiquejordannunesribeiro intentiontouseprepamongmenwhohavesexwithmenandengageinchemsexaninternationaldescriptivestudy AT guilhermereisdesantanasantos intentiontouseprepamongmenwhohavesexwithmenandengageinchemsexaninternationaldescriptivestudy AT layzebrazdeoliveira intentiontouseprepamongmenwhohavesexwithmenandengageinchemsexaninternationaldescriptivestudy AT emersonlucassilvacamargo intentiontouseprepamongmenwhohavesexwithmenandengageinchemsexaninternationaldescriptivestudy AT shirleyveronicameloalmeidalima intentiontouseprepamongmenwhohavesexwithmenandengageinchemsexaninternationaldescriptivestudy AT inaravivianedeoliveirasena intentiontouseprepamongmenwhohavesexwithmenandengageinchemsexaninternationaldescriptivestudy AT marciobezerrasantos intentiontouseprepamongmenwhohavesexwithmenandengageinchemsexaninternationaldescriptivestudy AT odineamariaamorimbatista intentiontouseprepamongmenwhohavesexwithmenandengageinchemsexaninternationaldescriptivestudy AT andersonreisdesousa intentiontouseprepamongmenwhohavesexwithmenandengageinchemsexaninternationaldescriptivestudy AT isabelameliacostamendes intentiontouseprepamongmenwhohavesexwithmenandengageinchemsexaninternationaldescriptivestudy |