Measurement of Instantaneous Wave-free Ratio through a Diagnostic Catheter: Comparison of the Results between 4Fr and 5Fr
Background: Clinical evidence of coronary pressure assessment through a diagnostic catheter is limited. The aim of this study was to assess the difference, safety, and rate of successful measurement of Instantaneous Wave-free Ratio (iFR) through 4Fr and 5Fr diagnostic catheters. Methods: This singl...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2020-06-01
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| Series: | Artery Research |
| Subjects: | |
| Online Access: | https://www.atlantis-press.com/article/125941523/view |
| _version_ | 1818140253817405440 |
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| author | Shinichiro Masuda Ryota Uemura Yoshiyuki Saiki Tatsuo Haraki Takeshi Lee |
| author_facet | Shinichiro Masuda Ryota Uemura Yoshiyuki Saiki Tatsuo Haraki Takeshi Lee |
| author_sort | Shinichiro Masuda |
| collection | DOAJ |
| description | Background: Clinical evidence of coronary pressure assessment through a diagnostic catheter is limited. The aim of this study was to assess the difference, safety, and rate of successful measurement of Instantaneous Wave-free Ratio (iFR) through 4Fr and 5Fr diagnostic catheters.
Methods: This single-centre prospective study included 32 lesions among 24 patients exhibiting intermediate coronary stenosis on coronary angiography. iFR measurements were performed through 4Fr and 5Fr diagnostic catheters for each lesion. The primary outcome was the reliability, as assessed by a Bland–Altman plot, for comparison of the mean differences [mean ± 2 Standard Deviations (SDs)], and the agreement on the Kappa coefficient, using a threshold iFR value of 0.89. The secondary outcome was the rate of successful iFR measurement. Safety was assessed by procedural complications and in-hospital Major Adverse Cardiac Events (MACE).
Results: The mean difference was −0.0003 ± 0.058, according to the Bland–Altman plot. One lesion was out of the range of 2 SDs. There was good agreement (Kappa coefficient = 0.85), and the correlation coefficient between the 4Fr and 5Fr catheters was 0.948 (p < 0.001). The success rate was not significantly different between the 4Fr and 5Fr catheters (90.6% vs. 96.9%, p = 0.09), although the 4Fr catheter had a lower success rate. No procedural complications or in-hospital MACE occurred.
Conclusion: Our findings suggest that iFR measurements could be safely performed, with similar reliability and success rate, through either the 4Fr or 5Fr diagnostic catheter.
•Instantaneous Wave-free Ratio (iFR) measurements through 4Fr and 5Fr diagnostic catheters.
•Correlation and agreement of iFR between 4Fr and 5Fr.
•To compare the successful measurement of iFR values. |
| first_indexed | 2024-12-11T10:41:03Z |
| format | Article |
| id | doaj.art-25d67cd4ae3b498a8fee553d91fe150a |
| institution | Directory Open Access Journal |
| issn | 1876-4401 |
| language | English |
| last_indexed | 2024-12-11T10:41:03Z |
| publishDate | 2020-06-01 |
| publisher | BMC |
| record_format | Article |
| series | Artery Research |
| spelling | doaj.art-25d67cd4ae3b498a8fee553d91fe150a2022-12-22T01:10:34ZengBMCArtery Research1876-44012020-06-0126310.2991/artres.k.200620.001Measurement of Instantaneous Wave-free Ratio through a Diagnostic Catheter: Comparison of the Results between 4Fr and 5FrShinichiro MasudaRyota UemuraYoshiyuki SaikiTatsuo HarakiTakeshi LeeBackground: Clinical evidence of coronary pressure assessment through a diagnostic catheter is limited. The aim of this study was to assess the difference, safety, and rate of successful measurement of Instantaneous Wave-free Ratio (iFR) through 4Fr and 5Fr diagnostic catheters. Methods: This single-centre prospective study included 32 lesions among 24 patients exhibiting intermediate coronary stenosis on coronary angiography. iFR measurements were performed through 4Fr and 5Fr diagnostic catheters for each lesion. The primary outcome was the reliability, as assessed by a Bland–Altman plot, for comparison of the mean differences [mean ± 2 Standard Deviations (SDs)], and the agreement on the Kappa coefficient, using a threshold iFR value of 0.89. The secondary outcome was the rate of successful iFR measurement. Safety was assessed by procedural complications and in-hospital Major Adverse Cardiac Events (MACE). Results: The mean difference was −0.0003 ± 0.058, according to the Bland–Altman plot. One lesion was out of the range of 2 SDs. There was good agreement (Kappa coefficient = 0.85), and the correlation coefficient between the 4Fr and 5Fr catheters was 0.948 (p < 0.001). The success rate was not significantly different between the 4Fr and 5Fr catheters (90.6% vs. 96.9%, p = 0.09), although the 4Fr catheter had a lower success rate. No procedural complications or in-hospital MACE occurred. Conclusion: Our findings suggest that iFR measurements could be safely performed, with similar reliability and success rate, through either the 4Fr or 5Fr diagnostic catheter. •Instantaneous Wave-free Ratio (iFR) measurements through 4Fr and 5Fr diagnostic catheters. •Correlation and agreement of iFR between 4Fr and 5Fr. •To compare the successful measurement of iFR values.https://www.atlantis-press.com/article/125941523/viewInstantaneous wave-free ratiopressure studyreliabilitydiagnostic catheter |
| spellingShingle | Shinichiro Masuda Ryota Uemura Yoshiyuki Saiki Tatsuo Haraki Takeshi Lee Measurement of Instantaneous Wave-free Ratio through a Diagnostic Catheter: Comparison of the Results between 4Fr and 5Fr Artery Research Instantaneous wave-free ratio pressure study reliability diagnostic catheter |
| title | Measurement of Instantaneous Wave-free Ratio through a Diagnostic Catheter: Comparison of the Results between 4Fr and 5Fr |
| title_full | Measurement of Instantaneous Wave-free Ratio through a Diagnostic Catheter: Comparison of the Results between 4Fr and 5Fr |
| title_fullStr | Measurement of Instantaneous Wave-free Ratio through a Diagnostic Catheter: Comparison of the Results between 4Fr and 5Fr |
| title_full_unstemmed | Measurement of Instantaneous Wave-free Ratio through a Diagnostic Catheter: Comparison of the Results between 4Fr and 5Fr |
| title_short | Measurement of Instantaneous Wave-free Ratio through a Diagnostic Catheter: Comparison of the Results between 4Fr and 5Fr |
| title_sort | measurement of instantaneous wave free ratio through a diagnostic catheter comparison of the results between 4fr and 5fr |
| topic | Instantaneous wave-free ratio pressure study reliability diagnostic catheter |
| url | https://www.atlantis-press.com/article/125941523/view |
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