Dysregulated autophagy-related genes in septic cardiomyopathy: Comprehensive bioinformatics analysis based on the human transcriptomes and experimental validation

Dysregulated autophagy-related genes in septic cardiomyopathy: Comprehensive bioinformatics analysis based on the human transcriptomes and experimental validation

Septic cardiomyopathy (SCM) is severe organ dysfunction caused by sepsis that is associated with poor prognosis, and its pathobiological mechanisms remain unclear. Autophagy is a biological process that has recently been focused on SCM, yet the current understanding of the role of dysregulated autop...

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Bibliographic Details
Main Authors: Hua-Xi Zou, Bai-Quan Qiu, Ze-Yu Zhang, Tie Hu, Li Wan, Ji-Chun Liu, Huang Huang, Song-Qing Lai
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
sepsis cardiomyopathy
autophagy
transcriptome
key genes
database
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2022.923066/full

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