Predicting protein folds with fold-specific PSSM libraries.

Accurately assigning folds for divergent protein sequences is a major obstacle to structural studies. Herein, we outline an effective method for fold recognition using sets of PSSMs, each of which is constructed for different protein folds. Our analyses demonstrate that FSL (Fold-specific Position S...

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Bibliographic Details
Main Authors: Yoojin Hong, Sree Vamsee Chintapalli, Kyung Dae Ko, Gaurav Bhardwaj, Zhenhai Zhang, Damian van Rossum, Randen L Patterson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3116844?pdf=render