The Dementia Rating Scale (DRS) in the diagnosis of vascular dementia

Abstract The Dementia Rating Scale (DRS) is considered a very useful instrument to assess patients with dementia. The tasks are grouped into five subscales, each one evaluating different cognitive areas, namely: Attention, Initiation/Perseveration (I/P), Construction, Conceptualization and Memory. O...

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Main Authors: Cláudia Sellitto Porto, Paulo Caramelli, Ricardo Nitrini
Format: Article
Language:English
Published: Associação Neurologia Cognitiva e do Comportamento
Series:Dementia & Neuropsychologia
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1980-57642007000300282&lng=en&tlng=en
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author Cláudia Sellitto Porto
Paulo Caramelli
Ricardo Nitrini
author_facet Cláudia Sellitto Porto
Paulo Caramelli
Ricardo Nitrini
author_sort Cláudia Sellitto Porto
collection DOAJ
description Abstract The Dementia Rating Scale (DRS) is considered a very useful instrument to assess patients with dementia. The tasks are grouped into five subscales, each one evaluating different cognitive areas, namely: Attention, Initiation/Perseveration (I/P), Construction, Conceptualization and Memory. Objective: To verify the ability of the DRS in discriminating vascular dementia (VaD) patients from healthy controls and VaD from Alzheimer disease (AD) patients. Methods: The DRS was applied to 68 patients with mild dementia (12 with VaD and 56 with AD) and 60 healthy controls. The clinical diagnosis was made by two neurologists based on the patients´ history, laboratory and neuroimaging results and neuropsychological tests. Results: In the comparison between VaD patients and controls, the subscales I/P, Memory, Conceptualization and Attention were those displaying best discrimination between the two groups. The cutoff <124 yielded 93.3% of sensitivity and 91.7% of specificity for the diagnosis of VaD. Only the I/P subscale differentiated VaD from AD patients. Conclusions: The DRS was found to be a useful instrument to discriminate VaD patients from controls. VaD patients showed worse performance in tasks of executive functions than AD patients. Executive dysfunction, evaluated through the I/P subscale of the DRS, might be useful in differentiating between VaD and AD patients.
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spelling doaj.art-25db7f72616b40e2907146de3c7219a32022-12-22T00:13:33ZengAssociação Neurologia Cognitiva e do ComportamentoDementia & Neuropsychologia1980-57641328228710.1590/S1980-57642008DN10300010S1980-57642007000300282The Dementia Rating Scale (DRS) in the diagnosis of vascular dementiaCláudia Sellitto PortoPaulo CaramelliRicardo NitriniAbstract The Dementia Rating Scale (DRS) is considered a very useful instrument to assess patients with dementia. The tasks are grouped into five subscales, each one evaluating different cognitive areas, namely: Attention, Initiation/Perseveration (I/P), Construction, Conceptualization and Memory. Objective: To verify the ability of the DRS in discriminating vascular dementia (VaD) patients from healthy controls and VaD from Alzheimer disease (AD) patients. Methods: The DRS was applied to 68 patients with mild dementia (12 with VaD and 56 with AD) and 60 healthy controls. The clinical diagnosis was made by two neurologists based on the patients´ history, laboratory and neuroimaging results and neuropsychological tests. Results: In the comparison between VaD patients and controls, the subscales I/P, Memory, Conceptualization and Attention were those displaying best discrimination between the two groups. The cutoff <124 yielded 93.3% of sensitivity and 91.7% of specificity for the diagnosis of VaD. Only the I/P subscale differentiated VaD from AD patients. Conclusions: The DRS was found to be a useful instrument to discriminate VaD patients from controls. VaD patients showed worse performance in tasks of executive functions than AD patients. Executive dysfunction, evaluated through the I/P subscale of the DRS, might be useful in differentiating between VaD and AD patients.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1980-57642007000300282&lng=en&tlng=endementianeuropsychological testscognitive disordersAlzheimer diseasevascular dementia.
spellingShingle Cláudia Sellitto Porto
Paulo Caramelli
Ricardo Nitrini
The Dementia Rating Scale (DRS) in the diagnosis of vascular dementia
Dementia & Neuropsychologia
dementia
neuropsychological tests
cognitive disorders
Alzheimer disease
vascular dementia.
title The Dementia Rating Scale (DRS) in the diagnosis of vascular dementia
title_full The Dementia Rating Scale (DRS) in the diagnosis of vascular dementia
title_fullStr The Dementia Rating Scale (DRS) in the diagnosis of vascular dementia
title_full_unstemmed The Dementia Rating Scale (DRS) in the diagnosis of vascular dementia
title_short The Dementia Rating Scale (DRS) in the diagnosis of vascular dementia
title_sort dementia rating scale drs in the diagnosis of vascular dementia
topic dementia
neuropsychological tests
cognitive disorders
Alzheimer disease
vascular dementia.
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1980-57642007000300282&lng=en&tlng=en
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