Effects of anti-inflammatory drugs on fever and neutrophilia induced by Clostridium difficile toxin B
This study investigated the ability of Clostridium difficile toxin B, isolated from the VPI 10463 strain, to induce fever and neutrophilia in rats. Intravenous injection of toxin B (0.005–0.5 μg/kg) evoked a dose-dependent increase in body temperature. The febrile response to 0.5 μg/kg of the toxin...
| Hauptverfasser: | , , , , , , , |
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| Format: | Artikel |
| Sprache: | English |
| Veröffentlicht: |
Wiley
1996-01-01
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| Schriftenreihe: | Mediators of Inflammation |
| Online Zugang: | http://dx.doi.org/10.1155/S0962935196000245 |