Vestibular effects of a 7 Tesla MRI examination compared to 1.5 T and 0 T in healthy volunteers.
Ultra-high-field MRI (7 Tesla (T) and above) elicits more temporary side-effects compared to 1.5 T and 3 T, e.g. dizziness or "postural instability" even after exiting the scanner. The current study aims to assess quantitatively vestibular performance before and after exposure to different...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2014-01-01
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| Series: | PLoS ONE |
| Online Access: | http://europepmc.org/articles/PMC3962400?pdf=render |
| _version_ | 1818961070356692992 |
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| author | Jens M Theysohn Oliver Kraff Kristina Eilers Dorian Andrade Marcus Gerwig Dagmar Timmann Franz Schmitt Mark E Ladd Susanne C Ladd Andreas K Bitz |
| author_facet | Jens M Theysohn Oliver Kraff Kristina Eilers Dorian Andrade Marcus Gerwig Dagmar Timmann Franz Schmitt Mark E Ladd Susanne C Ladd Andreas K Bitz |
| author_sort | Jens M Theysohn |
| collection | DOAJ |
| description | Ultra-high-field MRI (7 Tesla (T) and above) elicits more temporary side-effects compared to 1.5 T and 3 T, e.g. dizziness or "postural instability" even after exiting the scanner. The current study aims to assess quantitatively vestibular performance before and after exposure to different MRI scenarios at 7 T, 1.5 T and 0 T. Sway path and body axis rotation (Unterberger's stepping test) were quantitatively recorded in a total of 46 volunteers before, 2 minutes after, and 15 minutes after different exposure scenarios: 7 T head MRI (n = 27), 7 T no RF (n = 22), 7 T only B0 (n = 20), 7 T in & out B0 (n = 20), 1.5 T no RF (n = 20), 0 T (n = 15). All exposure scenarios lasted 30 minutes except for brief one minute exposure in 7 T in & out B0. Both measures were documented utilizing a 3D ultrasound system. During sway path evaluation, the experiment was repeated with eyes both open and closed. Sway paths for all long-lasting 7 T scenarios (normal, no RF, only B0) with eyes closed were significantly prolonged 2 minutes after exiting the scanner, normalizing after 15 minutes. Brief exposure to 7 T B0 or 30 minutes exposure to 1.5 T or 0 T did not show significant changes. End positions after Unterberger's stepping test were significantly changed counter-clockwise after all 7 T scenarios, including the brief in & out B0 exposure. Shorter exposure resulted in a smaller alteration angle. In contrast to sway path, reversal of changes in body axis rotation was incomplete after 15 minutes. 1.5 T caused no rotational changes. The results show that exposure to the 7 Tesla static magnetic field causes only a temporary dysfunction or "over-compensation" of the vestibular system not measurable at 1.5 or 0 Tesla. Radiofrequency fields, gradient switching, and orthostatic dysregulation do not seem to play a role. |
| first_indexed | 2024-12-20T12:07:35Z |
| format | Article |
| id | doaj.art-25e5509b67014bb2a2669cf06336eb55 |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-12-20T12:07:35Z |
| publishDate | 2014-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-25e5509b67014bb2a2669cf06336eb552022-12-21T19:41:20ZengPublic Library of Science (PLoS)PLoS ONE1932-62032014-01-0193e9210410.1371/journal.pone.0092104Vestibular effects of a 7 Tesla MRI examination compared to 1.5 T and 0 T in healthy volunteers.Jens M TheysohnOliver KraffKristina EilersDorian AndradeMarcus GerwigDagmar TimmannFranz SchmittMark E LaddSusanne C LaddAndreas K BitzUltra-high-field MRI (7 Tesla (T) and above) elicits more temporary side-effects compared to 1.5 T and 3 T, e.g. dizziness or "postural instability" even after exiting the scanner. The current study aims to assess quantitatively vestibular performance before and after exposure to different MRI scenarios at 7 T, 1.5 T and 0 T. Sway path and body axis rotation (Unterberger's stepping test) were quantitatively recorded in a total of 46 volunteers before, 2 minutes after, and 15 minutes after different exposure scenarios: 7 T head MRI (n = 27), 7 T no RF (n = 22), 7 T only B0 (n = 20), 7 T in & out B0 (n = 20), 1.5 T no RF (n = 20), 0 T (n = 15). All exposure scenarios lasted 30 minutes except for brief one minute exposure in 7 T in & out B0. Both measures were documented utilizing a 3D ultrasound system. During sway path evaluation, the experiment was repeated with eyes both open and closed. Sway paths for all long-lasting 7 T scenarios (normal, no RF, only B0) with eyes closed were significantly prolonged 2 minutes after exiting the scanner, normalizing after 15 minutes. Brief exposure to 7 T B0 or 30 minutes exposure to 1.5 T or 0 T did not show significant changes. End positions after Unterberger's stepping test were significantly changed counter-clockwise after all 7 T scenarios, including the brief in & out B0 exposure. Shorter exposure resulted in a smaller alteration angle. In contrast to sway path, reversal of changes in body axis rotation was incomplete after 15 minutes. 1.5 T caused no rotational changes. The results show that exposure to the 7 Tesla static magnetic field causes only a temporary dysfunction or "over-compensation" of the vestibular system not measurable at 1.5 or 0 Tesla. Radiofrequency fields, gradient switching, and orthostatic dysregulation do not seem to play a role.http://europepmc.org/articles/PMC3962400?pdf=render |
| spellingShingle | Jens M Theysohn Oliver Kraff Kristina Eilers Dorian Andrade Marcus Gerwig Dagmar Timmann Franz Schmitt Mark E Ladd Susanne C Ladd Andreas K Bitz Vestibular effects of a 7 Tesla MRI examination compared to 1.5 T and 0 T in healthy volunteers. PLoS ONE |
| title | Vestibular effects of a 7 Tesla MRI examination compared to 1.5 T and 0 T in healthy volunteers. |
| title_full | Vestibular effects of a 7 Tesla MRI examination compared to 1.5 T and 0 T in healthy volunteers. |
| title_fullStr | Vestibular effects of a 7 Tesla MRI examination compared to 1.5 T and 0 T in healthy volunteers. |
| title_full_unstemmed | Vestibular effects of a 7 Tesla MRI examination compared to 1.5 T and 0 T in healthy volunteers. |
| title_short | Vestibular effects of a 7 Tesla MRI examination compared to 1.5 T and 0 T in healthy volunteers. |
| title_sort | vestibular effects of a 7 tesla mri examination compared to 1 5 t and 0 t in healthy volunteers |
| url | http://europepmc.org/articles/PMC3962400?pdf=render |
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