Treatment of small intestinal bacterial overgrowth: Conventional antibiotic therapy and alternative therapy - probiotics and low FODMAP diet
Introduction and purpose of the study: Small intestinal bacterial overgrowth syndrome (SIBO) is a syndrome characterized by an increased number of bacteria in the small intestine. The condition causes many non-specific symptoms such as diarrhea, abdominal pain and bloating. The purpose of this stud...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Kazimierz Wielki University
2023-06-01
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| Series: | Journal of Education, Health and Sport |
| Subjects: | |
| Online Access: | https://apcz.umk.pl/JEHS/article/view/44006 |
| _version_ | 1797794476305940480 |
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| author | Maria Litwiniuk Marcin Zaniuk Kamil Hurkała Dominika Antonik Barbara Denys Karolina Góra Wojciech Zdziennicki Patryk Zimnicki Marta Lato Konrad Iberszer |
| author_facet | Maria Litwiniuk Marcin Zaniuk Kamil Hurkała Dominika Antonik Barbara Denys Karolina Góra Wojciech Zdziennicki Patryk Zimnicki Marta Lato Konrad Iberszer |
| author_sort | Maria Litwiniuk |
| collection | DOAJ |
| description |
Introduction and purpose of the study: Small intestinal bacterial overgrowth syndrome (SIBO) is a syndrome characterized by an increased number of bacteria in the small intestine. The condition causes many non-specific symptoms such as diarrhea, abdominal pain and bloating. The purpose of this study is to review the current knowledge regarding treatment options for SIBO.
Methodology: A literature review was conducted based on PubMed, GoogleScholar databases and American College of Gastroenterology (ACG) guidelines.
Current knowledge: SIBO is a heterogeneous syndrome. Symptoms of bacterial overgrowth include bloating, abdominal pain and abnormal bowel motility. In more severe cases, patients may experience malabsorption leading to weight loss and malnutrition. SIBO can occur in healthy individuals, but very often accompanies other conditions. The primary test for diagnosis is non-invasive lactulose or glucose breath tests. For treatment, the antibiotic rifaximin is preferred. It exhibits a broad spectrum of activity and a low toxicity profile. Treatment may also include diet therapy and the use of probiotics.
Summary: SIBO continues to be both a diagnostic and therapeutic problem. Effective treatment includes not only elimination of the bacteria but also treatment of predisposing conditions. Conclusions of the study show a positive effect of rifaximin on the reduction of SIBO symptoms and improvement of patients' quality of life. The use of certain probiotics has a proven effect. According to the currently available literature, the effectiveness of the low-FODMAP diet in SIBO is hypothetical and further studies are needed to unequivocally confirm its efficacy.
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| first_indexed | 2024-03-13T03:03:23Z |
| format | Article |
| id | doaj.art-25e9cbb20b9e4be785528518fe39be95 |
| institution | Directory Open Access Journal |
| issn | 2391-8306 |
| language | English |
| last_indexed | 2024-03-13T03:03:23Z |
| publishDate | 2023-06-01 |
| publisher | Kazimierz Wielki University |
| record_format | Article |
| series | Journal of Education, Health and Sport |
| spelling | doaj.art-25e9cbb20b9e4be785528518fe39be952023-06-27T10:46:47ZengKazimierz Wielki UniversityJournal of Education, Health and Sport2391-83062023-06-0141110.12775/JEHS.2023.41.01.005Treatment of small intestinal bacterial overgrowth: Conventional antibiotic therapy and alternative therapy - probiotics and low FODMAP dietMaria Litwiniuk0Marcin Zaniuk1Kamil Hurkała2Dominika Antonik3Barbara DenysKarolina Góra4Wojciech Zdziennicki5Patryk Zimnicki6Marta Lato7Konrad Iberszer8Wojewódzki Szpital Specjalistyczny im. Stefana Kardynała Wyszyńskiego Samodzielny Publiczny Zakład Opieki Zdrowotnej w Lublinie, Al. Kraśnicka 100, 20-718 Lublin, PolandSamodzielny Publiczny Zakład Opieki Zdrowotnej MSWiA w Lublinie, ul. Grenadierów 3, 20-331 Lublin, PolandSamodzielny Publiczny Szpital Wojewódzki im. Papieża Jana Pawła II w Zamościu, ul. Aleje Jana Pawła II 10, 22-400 Zamość, Poland5 Wojskowy Szpital Kliniczny z Polikliniką w Krakowie, ul. Wrocławska ⅓, 30-901 Kraków, PolandSamodzielny Publiczny Szpital Kliniczny nr 4, ul. Jaczewskiego 8, 20-954 Lublin, PolandUniwersytecki Szpital Kliniczny w Poznaniu - ul. Przybyszewskiego 49, 60-355 Poznań, PolandSamodzielny Publiczny Zakład Opieki Zdrowotnej MSWiA w Lublinie, ul. Grenadierów 3, 20-331 Lublin, PolandSamodzielny Publiczny Zakład Opieki Zdrowotnej MSWiA w Lublinie, ul. Grenadierów 3, 20-331 Lublin, PolandSamodzielny Publiczny Szpital Kliniczny nr 4, ul. Jaczewskiego 8, 20-954 Lublin, Poland Introduction and purpose of the study: Small intestinal bacterial overgrowth syndrome (SIBO) is a syndrome characterized by an increased number of bacteria in the small intestine. The condition causes many non-specific symptoms such as diarrhea, abdominal pain and bloating. The purpose of this study is to review the current knowledge regarding treatment options for SIBO. Methodology: A literature review was conducted based on PubMed, GoogleScholar databases and American College of Gastroenterology (ACG) guidelines. Current knowledge: SIBO is a heterogeneous syndrome. Symptoms of bacterial overgrowth include bloating, abdominal pain and abnormal bowel motility. In more severe cases, patients may experience malabsorption leading to weight loss and malnutrition. SIBO can occur in healthy individuals, but very often accompanies other conditions. The primary test for diagnosis is non-invasive lactulose or glucose breath tests. For treatment, the antibiotic rifaximin is preferred. It exhibits a broad spectrum of activity and a low toxicity profile. Treatment may also include diet therapy and the use of probiotics. Summary: SIBO continues to be both a diagnostic and therapeutic problem. Effective treatment includes not only elimination of the bacteria but also treatment of predisposing conditions. Conclusions of the study show a positive effect of rifaximin on the reduction of SIBO symptoms and improvement of patients' quality of life. The use of certain probiotics has a proven effect. According to the currently available literature, the effectiveness of the low-FODMAP diet in SIBO is hypothetical and further studies are needed to unequivocally confirm its efficacy. https://apcz.umk.pl/JEHS/article/view/44006SIBOsmall intestinal bacterial overgrowth syndromerifaximinprobioticslowFODMAP diet |
| spellingShingle | Maria Litwiniuk Marcin Zaniuk Kamil Hurkała Dominika Antonik Barbara Denys Karolina Góra Wojciech Zdziennicki Patryk Zimnicki Marta Lato Konrad Iberszer Treatment of small intestinal bacterial overgrowth: Conventional antibiotic therapy and alternative therapy - probiotics and low FODMAP diet Journal of Education, Health and Sport SIBO small intestinal bacterial overgrowth syndrome rifaximin probiotics lowFODMAP diet |
| title | Treatment of small intestinal bacterial overgrowth: Conventional antibiotic therapy and alternative therapy - probiotics and low FODMAP diet |
| title_full | Treatment of small intestinal bacterial overgrowth: Conventional antibiotic therapy and alternative therapy - probiotics and low FODMAP diet |
| title_fullStr | Treatment of small intestinal bacterial overgrowth: Conventional antibiotic therapy and alternative therapy - probiotics and low FODMAP diet |
| title_full_unstemmed | Treatment of small intestinal bacterial overgrowth: Conventional antibiotic therapy and alternative therapy - probiotics and low FODMAP diet |
| title_short | Treatment of small intestinal bacterial overgrowth: Conventional antibiotic therapy and alternative therapy - probiotics and low FODMAP diet |
| title_sort | treatment of small intestinal bacterial overgrowth conventional antibiotic therapy and alternative therapy probiotics and low fodmap diet |
| topic | SIBO small intestinal bacterial overgrowth syndrome rifaximin probiotics lowFODMAP diet |
| url | https://apcz.umk.pl/JEHS/article/view/44006 |
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