Risk factor for interstitial pregnancy following ipsilateral salpingectomy? A retrospective matched case control study
Abstract Background Interstitial pregnancy may still happen even after ipsilateral salpingectomy, resulting in massive hemorrhage. Therefore, the purpose of the study is to identify risk factors associated with interstitial pregnancy following ipsilateral salpingectomy and discuss possible preventio...
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| Format: | Article |
| Language: | English |
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BMC
2023-11-01
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| Series: | BMC Pregnancy and Childbirth |
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| Online Access: | https://doi.org/10.1186/s12884-023-06132-0 |
| _version_ | 1797413637200019456 |
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| author | Wei-Fang Wu Jing-Song Yi Xi Xie Chao-Bin Liu |
| author_facet | Wei-Fang Wu Jing-Song Yi Xi Xie Chao-Bin Liu |
| author_sort | Wei-Fang Wu |
| collection | DOAJ |
| description | Abstract Background Interstitial pregnancy may still happen even after ipsilateral salpingectomy, resulting in massive hemorrhage. Therefore, the purpose of the study is to identify risk factors associated with interstitial pregnancy following ipsilateral salpingectomy and discuss possible prevention. Methods We conducted a retrospective cohort study in a single, large, university-affiliated hospital. Data of 29 patients diagnosed with interstitial pregnancy following ipsilateral salpingectomy from January 2011 to November 2020 were assigned into the case group (IP group). Whereas there were 6151 patients with intrauterine pregnancy after unilateral salpingectomy in the same period. A sample size of 87 control patients was calculated to achieve statistical power (99.9%) and an α of 0.05. The age, BMI and previous salpingectomy side between the two group were adjusted with PSM at a ratio of 1:3. After PSM, 87 intrauterine pregnancy patients were successfully matched to 29 IP patients. Results After PSM, parous women were more common and intrauterine operation was more frequent in the IP group compared with control group (P<0.05). There was only one patient undergoing IVF-ET in the IP group as compared with 29 cases in the control group (3.4% vs. 33.3%, P<0.05). Salpingectomy was performed on 5 patients in the IP group and 4 patients in the control group due to hydrosalpinx (P<0.05). Logistic regression indicated that hydrosalpinx was the high risk factor of interstitial pregnancy following ipsilateral salpingectomy (OR = 8.175). Conclusions Hydrosalpinx appears to be an independent factor contributing to interstitial pregnancy following ipsilateral salpingectomy in subsequent pregnancy. |
| first_indexed | 2024-03-09T05:21:53Z |
| format | Article |
| id | doaj.art-25ebba3402394e959c25930f0a047942 |
| institution | Directory Open Access Journal |
| issn | 1471-2393 |
| language | English |
| last_indexed | 2024-03-09T05:21:53Z |
| publishDate | 2023-11-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Pregnancy and Childbirth |
| spelling | doaj.art-25ebba3402394e959c25930f0a0479422023-12-03T12:39:48ZengBMCBMC Pregnancy and Childbirth1471-23932023-11-012311610.1186/s12884-023-06132-0Risk factor for interstitial pregnancy following ipsilateral salpingectomy? A retrospective matched case control studyWei-Fang Wu0Jing-Song Yi1Xi Xie2Chao-Bin Liu3Department of Obstetrics and Gynecology, Fujian Maternity and Child Health Hospital, College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical UniversityDepartment of Obstetrics and Gynecology, Fujian Maternity and Child Health Hospital, College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical UniversityDepartment of Obstetrics and Gynecology, Fujian Maternity and Child Health Hospital, College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical UniversityDepartment of Obstetrics and Gynecology, Fujian Maternity and Child Health Hospital, College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical UniversityAbstract Background Interstitial pregnancy may still happen even after ipsilateral salpingectomy, resulting in massive hemorrhage. Therefore, the purpose of the study is to identify risk factors associated with interstitial pregnancy following ipsilateral salpingectomy and discuss possible prevention. Methods We conducted a retrospective cohort study in a single, large, university-affiliated hospital. Data of 29 patients diagnosed with interstitial pregnancy following ipsilateral salpingectomy from January 2011 to November 2020 were assigned into the case group (IP group). Whereas there were 6151 patients with intrauterine pregnancy after unilateral salpingectomy in the same period. A sample size of 87 control patients was calculated to achieve statistical power (99.9%) and an α of 0.05. The age, BMI and previous salpingectomy side between the two group were adjusted with PSM at a ratio of 1:3. After PSM, 87 intrauterine pregnancy patients were successfully matched to 29 IP patients. Results After PSM, parous women were more common and intrauterine operation was more frequent in the IP group compared with control group (P<0.05). There was only one patient undergoing IVF-ET in the IP group as compared with 29 cases in the control group (3.4% vs. 33.3%, P<0.05). Salpingectomy was performed on 5 patients in the IP group and 4 patients in the control group due to hydrosalpinx (P<0.05). Logistic regression indicated that hydrosalpinx was the high risk factor of interstitial pregnancy following ipsilateral salpingectomy (OR = 8.175). Conclusions Hydrosalpinx appears to be an independent factor contributing to interstitial pregnancy following ipsilateral salpingectomy in subsequent pregnancy.https://doi.org/10.1186/s12884-023-06132-0Interstitial pregnancySalpingectomyHydrosalpinxPropensity score matchingRisk factor |
| spellingShingle | Wei-Fang Wu Jing-Song Yi Xi Xie Chao-Bin Liu Risk factor for interstitial pregnancy following ipsilateral salpingectomy? A retrospective matched case control study BMC Pregnancy and Childbirth Interstitial pregnancy Salpingectomy Hydrosalpinx Propensity score matching Risk factor |
| title | Risk factor for interstitial pregnancy following ipsilateral salpingectomy? A retrospective matched case control study |
| title_full | Risk factor for interstitial pregnancy following ipsilateral salpingectomy? A retrospective matched case control study |
| title_fullStr | Risk factor for interstitial pregnancy following ipsilateral salpingectomy? A retrospective matched case control study |
| title_full_unstemmed | Risk factor for interstitial pregnancy following ipsilateral salpingectomy? A retrospective matched case control study |
| title_short | Risk factor for interstitial pregnancy following ipsilateral salpingectomy? A retrospective matched case control study |
| title_sort | risk factor for interstitial pregnancy following ipsilateral salpingectomy a retrospective matched case control study |
| topic | Interstitial pregnancy Salpingectomy Hydrosalpinx Propensity score matching Risk factor |
| url | https://doi.org/10.1186/s12884-023-06132-0 |
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