A genetic screen identifies a role for oprF in Pseudomonas aeruginosa biofilm stimulation by subinhibitory antibiotics

Abstract Biofilms are surface-associated communities of bacteria that grow in a self-produced matrix of polysaccharides, proteins, and extracellular DNA (eDNA). Sub-minimal inhibitory concentrations (sub-MIC) of antibiotics induce biofilm formation, potentially as a defensive response to antibiotic...

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Bibliographic Details
Main Authors: Luke N. Yaeger, Michael R. M. Ranieri, Jessica Chee, Sawyer Karabelas-Pittman, Madeleine Rudolph, Alessio M. Giovannoni, Hanjeong Harvey, Lori L. Burrows
Format: Article
Language:English
Published: Nature Portfolio 2024-03-01
Series:npj Biofilms and Microbiomes
Online Access:https://doi.org/10.1038/s41522-024-00496-7

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