Suspected immune checkpoint inhibitor‐induced pulmonary sarcoid reaction in metastatic renal cell carcinoma
Abstract We present the case of a 50‐year‐old male patient with metastatic clear cell renal cell carcinoma (mRCC) who developed a diffuse pulmonary opacification and lymphadenopathy during nivolumab maintenance therapy. This was diagnosed as presumed sarcoid granulomatous inflammatory reaction secon...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Wiley
2022-07-01
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| Series: | Clinical Case Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/ccr3.5960 |
| _version_ | 1811312342924787712 |
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| author | Victoria Purcell Beatrice Preti Ricardo Fernandes |
| author_facet | Victoria Purcell Beatrice Preti Ricardo Fernandes |
| author_sort | Victoria Purcell |
| collection | DOAJ |
| description | Abstract We present the case of a 50‐year‐old male patient with metastatic clear cell renal cell carcinoma (mRCC) who developed a diffuse pulmonary opacification and lymphadenopathy during nivolumab maintenance therapy. This was diagnosed as presumed sarcoid granulomatous inflammatory reaction secondary to immunotherapy, which resolved with holding off therapy and the nivolumab was resumed. |
| first_indexed | 2024-04-13T10:35:39Z |
| format | Article |
| id | doaj.art-25f07734dd5143afb77f18428a371aca |
| institution | Directory Open Access Journal |
| issn | 2050-0904 |
| language | English |
| last_indexed | 2024-04-13T10:35:39Z |
| publishDate | 2022-07-01 |
| publisher | Wiley |
| record_format | Article |
| series | Clinical Case Reports |
| spelling | doaj.art-25f07734dd5143afb77f18428a371aca2022-12-22T02:50:04ZengWileyClinical Case Reports2050-09042022-07-01107n/an/a10.1002/ccr3.5960Suspected immune checkpoint inhibitor‐induced pulmonary sarcoid reaction in metastatic renal cell carcinomaVictoria Purcell0Beatrice Preti1Ricardo Fernandes2Schulich School of Medicine and Dentistry Western University London Ontario CanadaSchulich School of Medicine and Dentistry Western University London Ontario CanadaSchulich School of Medicine and Dentistry Western University London Ontario CanadaAbstract We present the case of a 50‐year‐old male patient with metastatic clear cell renal cell carcinoma (mRCC) who developed a diffuse pulmonary opacification and lymphadenopathy during nivolumab maintenance therapy. This was diagnosed as presumed sarcoid granulomatous inflammatory reaction secondary to immunotherapy, which resolved with holding off therapy and the nivolumab was resumed.https://doi.org/10.1002/ccr3.5960immune‐related adverse eventsimmunotherapymetastatic renal cell carcinomasarcoid‐like reactions |
| spellingShingle | Victoria Purcell Beatrice Preti Ricardo Fernandes Suspected immune checkpoint inhibitor‐induced pulmonary sarcoid reaction in metastatic renal cell carcinoma Clinical Case Reports immune‐related adverse events immunotherapy metastatic renal cell carcinoma sarcoid‐like reactions |
| title | Suspected immune checkpoint inhibitor‐induced pulmonary sarcoid reaction in metastatic renal cell carcinoma |
| title_full | Suspected immune checkpoint inhibitor‐induced pulmonary sarcoid reaction in metastatic renal cell carcinoma |
| title_fullStr | Suspected immune checkpoint inhibitor‐induced pulmonary sarcoid reaction in metastatic renal cell carcinoma |
| title_full_unstemmed | Suspected immune checkpoint inhibitor‐induced pulmonary sarcoid reaction in metastatic renal cell carcinoma |
| title_short | Suspected immune checkpoint inhibitor‐induced pulmonary sarcoid reaction in metastatic renal cell carcinoma |
| title_sort | suspected immune checkpoint inhibitor induced pulmonary sarcoid reaction in metastatic renal cell carcinoma |
| topic | immune‐related adverse events immunotherapy metastatic renal cell carcinoma sarcoid‐like reactions |
| url | https://doi.org/10.1002/ccr3.5960 |
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