The relationship between low-birth weight and nephrotic syndrome in children
Introduction: The body weight of an infant is one of the most important factors that influences its survival, growth and development. Many clinical studies have shown a higher risk of an aggravated course of renal disease in children born with low- birth weight (LBW), due to reduction in glomerular...
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| Format: | Article |
| Language: | English |
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Society of Diabetic Nephropathy Prevention
2018-01-01
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| Series: | Journal of Nephropharmacology |
| Subjects: | |
| Online Access: | http://jnephropharmacology.com/PDF/npj-7-6.pdf |
| _version_ | 1818038391913054208 |
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| author | Negin Rezavand Abolhassan Seyedzadeh Mohammad-Reza Tohidi Mohammad-Saleh Seyedzadeh Sara Hookary Alireza Abdi |
| author_facet | Negin Rezavand Abolhassan Seyedzadeh Mohammad-Reza Tohidi Mohammad-Saleh Seyedzadeh Sara Hookary Alireza Abdi |
| author_sort | Negin Rezavand |
| collection | DOAJ |
| description | Introduction: The body weight of an infant is one of the most important factors that influences its survival, growth and development. Many clinical studies have shown a higher risk of an aggravated course of renal disease in children born with low- birth weight (LBW), due to reduction in glomerular number and development. However, there are limited clinical studies about this relationship.
Objectives: This study was conducted to evaluate the relationship between LBW and risk of idiopathic nephrotic syndrome (INS) in children.
Patients and Methods: In this case–control study, we evaluated nephrotic syndrome patients who were referred to Imam Raza hospital. Seventy patients with nephrotic syndrome as case group and 140 healthy children under age 16 with normal birth weight as control group were enrolled in the study. Data including age, sex, and birth weight were collected from patient’s records.
Results: This study revealed that the risk of nephrotic syndrome in patients with LBW is two times higher than those with normal birth weight. However, there was no statistically significant difference (χ2 = 1.58, P = 0.12)
Conclusion: Although the result of this study cannot show a statistically significant relationship between INS and LBW, the risk of nephrotic syndrome was twice in the case group. |
| first_indexed | 2024-12-10T07:42:00Z |
| format | Article |
| id | doaj.art-25f086eb560e4e1989abc931ac73d07c |
| institution | Directory Open Access Journal |
| issn | 2345-4202 |
| language | English |
| last_indexed | 2024-12-10T07:42:00Z |
| publishDate | 2018-01-01 |
| publisher | Society of Diabetic Nephropathy Prevention |
| record_format | Article |
| series | Journal of Nephropharmacology |
| spelling | doaj.art-25f086eb560e4e1989abc931ac73d07c2022-12-22T01:57:16ZengSociety of Diabetic Nephropathy PreventionJournal of Nephropharmacology2345-42022018-01-01716910.15171/npj.2018.03npj-20180227115929The relationship between low-birth weight and nephrotic syndrome in childrenNegin Rezavand0Abolhassan Seyedzadeh1Mohammad-Reza Tohidi2Mohammad-Saleh Seyedzadeh3Sara Hookary4Alireza Abdi5Department of Gynecology and Obstetrics, Kermanshah University of Medical Sciences, Kermanshah, IranUrology and Nephrology Research Center, Kermanshah University of Medical Sciences, Kermanshah, IranUrology and Nephrology Research Center, Kermanshah University of Medical Sciences, Kermanshah, IranUrology and Nephrology Research Center, Kermanshah University of Medical Sciences, Kermanshah, IranUrology and Nephrology Research Center, Kermanshah University of Medical Sciences, Kermanshah, IranNursing and Midwifery School, Kermanshah University of Medical Sciences, Kermanshah, IranIntroduction: The body weight of an infant is one of the most important factors that influences its survival, growth and development. Many clinical studies have shown a higher risk of an aggravated course of renal disease in children born with low- birth weight (LBW), due to reduction in glomerular number and development. However, there are limited clinical studies about this relationship. Objectives: This study was conducted to evaluate the relationship between LBW and risk of idiopathic nephrotic syndrome (INS) in children. Patients and Methods: In this case–control study, we evaluated nephrotic syndrome patients who were referred to Imam Raza hospital. Seventy patients with nephrotic syndrome as case group and 140 healthy children under age 16 with normal birth weight as control group were enrolled in the study. Data including age, sex, and birth weight were collected from patient’s records. Results: This study revealed that the risk of nephrotic syndrome in patients with LBW is two times higher than those with normal birth weight. However, there was no statistically significant difference (χ2 = 1.58, P = 0.12) Conclusion: Although the result of this study cannot show a statistically significant relationship between INS and LBW, the risk of nephrotic syndrome was twice in the case group.http://jnephropharmacology.com/PDF/npj-7-6.pdfIdiopathic nephrotic syndromeLow-birth weightGlomerular development |
| spellingShingle | Negin Rezavand Abolhassan Seyedzadeh Mohammad-Reza Tohidi Mohammad-Saleh Seyedzadeh Sara Hookary Alireza Abdi The relationship between low-birth weight and nephrotic syndrome in children Journal of Nephropharmacology Idiopathic nephrotic syndrome Low-birth weight Glomerular development |
| title | The relationship between low-birth weight and nephrotic syndrome in children |
| title_full | The relationship between low-birth weight and nephrotic syndrome in children |
| title_fullStr | The relationship between low-birth weight and nephrotic syndrome in children |
| title_full_unstemmed | The relationship between low-birth weight and nephrotic syndrome in children |
| title_short | The relationship between low-birth weight and nephrotic syndrome in children |
| title_sort | relationship between low birth weight and nephrotic syndrome in children |
| topic | Idiopathic nephrotic syndrome Low-birth weight Glomerular development |
| url | http://jnephropharmacology.com/PDF/npj-7-6.pdf |
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