Inhibition of TRPA1, Endoplasmic Reticulum Stress, Human Airway Epithelial Cell Damage, and Ectopic <i>MUC5AC</i> Expression by Vasaka (<i>Adhatoda vasica</i>; Malabar Nut) Tea

Inhibition of TRPA1, Endoplasmic Reticulum Stress, Human Airway Epithelial Cell Damage, and Ectopic <i>MUC5AC</i> Expression by Vasaka (<i>Adhatoda vasica</i>; Malabar Nut) Tea

This study tested whether a medicinal plant, Vasaka, typically consumed as a tea to treat respiratory malaise, could protect airway epithelial cells (AECs) from wood smoke particle-induced damage and prevent pathological mucus production. Wood/biomass smoke is a pneumotoxic air pollutant. Mucus norm...

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Bibliographic Details
Main Authors: Tosifa A. Memon, Lili Sun, Marysol Almestica-Roberts, Cassandra E. Deering-Rice, Philip J. Moos, Christopher A. Reilly
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Pharmaceuticals
Subjects:
Vasaka
TRPA1
airway epithelium
mucus hypersecretion
<i>MUC5AC</i>
lung injury
Online Access:https://www.mdpi.com/1424-8247/16/6/890

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