Isolation of dengue 2 virus from a patient with central nervous system involvement (transverse myelitis)
A dengue fever case is described in a 58-year-old male patient with febrile illness and thrombocytopenia complicated by neurological involvement characterized by transverse myelitis followed by weakness of both legs and flaccid paralysis. Muscle strength was much diminished and bilateral areflexia w...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Sociedade Brasileira de Medicina Tropical (SBMT)
2002-01-01
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| Series: | Revista da Sociedade Brasileira de Medicina Tropical |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822002000400018 |
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| author | Leão Raimundo N.Q. Oikawa Teichi Rosa Elizabeth S.T. Yamaki José T. Rodrigues Sueli G. Vasconcelos Helena B. Sousa Maria R.S. Tsukimata Jaime K. Azevedo Raimunda S.S. Vasconcelos Pedro F.C. |
| author_facet | Leão Raimundo N.Q. Oikawa Teichi Rosa Elizabeth S.T. Yamaki José T. Rodrigues Sueli G. Vasconcelos Helena B. Sousa Maria R.S. Tsukimata Jaime K. Azevedo Raimunda S.S. Vasconcelos Pedro F.C. |
| author_sort | Leão Raimundo N.Q. |
| collection | DOAJ |
| description | A dengue fever case is described in a 58-year-old male patient with febrile illness and thrombocytopenia complicated by neurological involvement characterized by transverse myelitis followed by weakness of both legs and flaccid paralysis. Muscle strength was much diminished and bilateral areflexia was observed. Dengue 2 (DEN-2) virus was isolated and the patient sero-converted by hemagglutination-inhibition and IgM-ELISA tests. The RT-PCR test was positive to DEN-2 in acute phase serum and culture supernatant, but negative in the cerebrospinal fluid. After three weeks of hospitalization the patient was discharged. No other infectious agent was detected in the blood and cerebrospinal fluid samples. The patient had full recovery from paralysis six months after the onset of DEN-2 infection. |
| first_indexed | 2024-04-13T20:46:55Z |
| format | Article |
| id | doaj.art-25f2b0c33e574d2e8b969515cf202493 |
| institution | Directory Open Access Journal |
| issn | 0037-8682 1678-9849 |
| language | English |
| last_indexed | 2024-04-13T20:46:55Z |
| publishDate | 2002-01-01 |
| publisher | Sociedade Brasileira de Medicina Tropical (SBMT) |
| record_format | Article |
| series | Revista da Sociedade Brasileira de Medicina Tropical |
| spelling | doaj.art-25f2b0c33e574d2e8b969515cf2024932022-12-22T02:30:39ZengSociedade Brasileira de Medicina Tropical (SBMT)Revista da Sociedade Brasileira de Medicina Tropical0037-86821678-98492002-01-01354401404Isolation of dengue 2 virus from a patient with central nervous system involvement (transverse myelitis)Leão Raimundo N.Q.Oikawa TeichiRosa Elizabeth S.T.Yamaki José T.Rodrigues Sueli G.Vasconcelos Helena B.Sousa Maria R.S.Tsukimata Jaime K.Azevedo Raimunda S.S.Vasconcelos Pedro F.C.A dengue fever case is described in a 58-year-old male patient with febrile illness and thrombocytopenia complicated by neurological involvement characterized by transverse myelitis followed by weakness of both legs and flaccid paralysis. Muscle strength was much diminished and bilateral areflexia was observed. Dengue 2 (DEN-2) virus was isolated and the patient sero-converted by hemagglutination-inhibition and IgM-ELISA tests. The RT-PCR test was positive to DEN-2 in acute phase serum and culture supernatant, but negative in the cerebrospinal fluid. After three weeks of hospitalization the patient was discharged. No other infectious agent was detected in the blood and cerebrospinal fluid samples. The patient had full recovery from paralysis six months after the onset of DEN-2 infection.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822002000400018Dengue feverTransverse myelitisDengue 2Virus isolationRT-PCR |
| spellingShingle | Leão Raimundo N.Q. Oikawa Teichi Rosa Elizabeth S.T. Yamaki José T. Rodrigues Sueli G. Vasconcelos Helena B. Sousa Maria R.S. Tsukimata Jaime K. Azevedo Raimunda S.S. Vasconcelos Pedro F.C. Isolation of dengue 2 virus from a patient with central nervous system involvement (transverse myelitis) Revista da Sociedade Brasileira de Medicina Tropical Dengue fever Transverse myelitis Dengue 2 Virus isolation RT-PCR |
| title | Isolation of dengue 2 virus from a patient with central nervous system involvement (transverse myelitis) |
| title_full | Isolation of dengue 2 virus from a patient with central nervous system involvement (transverse myelitis) |
| title_fullStr | Isolation of dengue 2 virus from a patient with central nervous system involvement (transverse myelitis) |
| title_full_unstemmed | Isolation of dengue 2 virus from a patient with central nervous system involvement (transverse myelitis) |
| title_short | Isolation of dengue 2 virus from a patient with central nervous system involvement (transverse myelitis) |
| title_sort | isolation of dengue 2 virus from a patient with central nervous system involvement transverse myelitis |
| topic | Dengue fever Transverse myelitis Dengue 2 Virus isolation RT-PCR |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822002000400018 |
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