Is there an association between the familial form of generalized joint hypermobility and developmental dysplasia of the hip in children?
Background and Objectives: This study aimed to examine the association between the familial generalized joint hypermobility (GJH) and developmental dysplasia of the hip (DDH) in children. Materials and Methods: All infants and children included in this case (with DDH)–control study were examined for...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2021-01-01
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| Series: | Medical Journal of Babylon |
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| Online Access: | http://www.medjbabylon.org/article.asp?issn=1812-156X;year=2021;volume=18;issue=4;spage=333;epage=339;aulast=Doski |
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| author | Jagar Omar Doski Farman Ola Ali |
| author_facet | Jagar Omar Doski Farman Ola Ali |
| author_sort | Jagar Omar Doski |
| collection | DOAJ |
| description | Background and Objectives: This study aimed to examine the association between the familial generalized joint hypermobility (GJH) and developmental dysplasia of the hip (DDH) in children. Materials and Methods: All infants and children included in this case (with DDH)–control study were examined for features of GJH by the revised Beighton’s Test Scale (BTS), provided that they had no teratogenic or pathological causes of DDH or GJH. Results: Two hundred and eight participants were included in this study: 101 (48.6%) cases and 107 (51.4%) controls; age mean 16.57 [standard deviation (SD) 18.1] months; 61.1% (127) females and 38.9% (81) males. The odds ratio was 2.1 (95% confidence interval 1.197–3.679). The cases had a higher value of BTS score (mean = 4.7, SD = 3.015) when compared with the controls (mean = 3.42, SD = 3.448). The difference was statistically significant, but the correlation coefficient (r) between the study groups and BTS scores was weak (r = 0.194, P = 0.005). The correlation gained slight improvement by justification of the age to obtain homogeneity between the groups (r = 0.276, P < 0.001), but deteriorated and lost its significance when the sex was controlled as a confounder (r = 0.121, P = 0.082). There was a gradual increase in the mean BTS score from grade 1 to grade 4 of DDH but without a statistically significant value (r = 0,132, P = 0.128). Conclusion: The familial GJH has a weak positive correlation with DDH but cannot be considered as a possible risk factor for it. |
| first_indexed | 2024-12-24T01:29:10Z |
| format | Article |
| id | doaj.art-25f439be44f246d8b1c9e3dc7609510e |
| institution | Directory Open Access Journal |
| issn | 1812-156X 2312-6760 |
| language | English |
| last_indexed | 2024-12-24T01:29:10Z |
| publishDate | 2021-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Medical Journal of Babylon |
| spelling | doaj.art-25f439be44f246d8b1c9e3dc7609510e2022-12-21T17:22:25ZengWolters Kluwer Medknow PublicationsMedical Journal of Babylon1812-156X2312-67602021-01-0118433333910.4103/MJBL.MJBL_46_21Is there an association between the familial form of generalized joint hypermobility and developmental dysplasia of the hip in children?Jagar Omar DoskiFarman Ola AliBackground and Objectives: This study aimed to examine the association between the familial generalized joint hypermobility (GJH) and developmental dysplasia of the hip (DDH) in children. Materials and Methods: All infants and children included in this case (with DDH)–control study were examined for features of GJH by the revised Beighton’s Test Scale (BTS), provided that they had no teratogenic or pathological causes of DDH or GJH. Results: Two hundred and eight participants were included in this study: 101 (48.6%) cases and 107 (51.4%) controls; age mean 16.57 [standard deviation (SD) 18.1] months; 61.1% (127) females and 38.9% (81) males. The odds ratio was 2.1 (95% confidence interval 1.197–3.679). The cases had a higher value of BTS score (mean = 4.7, SD = 3.015) when compared with the controls (mean = 3.42, SD = 3.448). The difference was statistically significant, but the correlation coefficient (r) between the study groups and BTS scores was weak (r = 0.194, P = 0.005). The correlation gained slight improvement by justification of the age to obtain homogeneity between the groups (r = 0.276, P < 0.001), but deteriorated and lost its significance when the sex was controlled as a confounder (r = 0.121, P = 0.082). There was a gradual increase in the mean BTS score from grade 1 to grade 4 of DDH but without a statistically significant value (r = 0,132, P = 0.128). Conclusion: The familial GJH has a weak positive correlation with DDH but cannot be considered as a possible risk factor for it.http://www.medjbabylon.org/article.asp?issn=1812-156X;year=2021;volume=18;issue=4;spage=333;epage=339;aulast=Doskiassociationdevelopmental dysplasia of the hipgeneralized joint hypermobility |
| spellingShingle | Jagar Omar Doski Farman Ola Ali Is there an association between the familial form of generalized joint hypermobility and developmental dysplasia of the hip in children? Medical Journal of Babylon association developmental dysplasia of the hip generalized joint hypermobility |
| title | Is there an association between the familial form of generalized joint hypermobility and developmental dysplasia of the hip in children? |
| title_full | Is there an association between the familial form of generalized joint hypermobility and developmental dysplasia of the hip in children? |
| title_fullStr | Is there an association between the familial form of generalized joint hypermobility and developmental dysplasia of the hip in children? |
| title_full_unstemmed | Is there an association between the familial form of generalized joint hypermobility and developmental dysplasia of the hip in children? |
| title_short | Is there an association between the familial form of generalized joint hypermobility and developmental dysplasia of the hip in children? |
| title_sort | is there an association between the familial form of generalized joint hypermobility and developmental dysplasia of the hip in children |
| topic | association developmental dysplasia of the hip generalized joint hypermobility |
| url | http://www.medjbabylon.org/article.asp?issn=1812-156X;year=2021;volume=18;issue=4;spage=333;epage=339;aulast=Doski |
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