The role of Interleukin-6 (IL-6) in pathogensis of COVID -19

Dissimilar to all other pandemics in the past five decades, the humanity has been ravaged by the coronavirus disease COVID-19. Starting from its outbreak, the disease's understanding has advanced quickly; multi-organ involvement is the key factor affecting the prognosis of the disease. Mortali...

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Main Authors: Noorulhuda F. Khalaf, Sinai W. Mohammed, Ahmed Y. Hanoon
Format: Article
Language:English
Published: University of Thi-Qar 2023-06-01
Series:مجلة علوم ذي قار
Subjects:
Online Access:https://jsci.utq.edu.iq/index.php/main/article/view/895
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author Noorulhuda F. Khalaf
Sinai W. Mohammed
Ahmed Y. Hanoon
author_facet Noorulhuda F. Khalaf
Sinai W. Mohammed
Ahmed Y. Hanoon
author_sort Noorulhuda F. Khalaf
collection DOAJ
description Dissimilar to all other pandemics in the past five decades, the humanity has been ravaged by the coronavirus disease COVID-19. Starting from its outbreak, the disease's understanding has advanced quickly; multi-organ involvement is the key factor affecting the prognosis of the disease. Mortality and morbidity are closely related to acute respiratory distress syndrome, renal failure, cardiac failure, liver damage, multi-organ failure, and shock. In the initial phases of viral infection, detecting and controlling pro-inflammatory responses are essential. Throughout patient monitoring, it's crucial to consider the COVID-19 treatment's unknowable response. It has been discovered that IL-6 is causally linked to greater mortality. It is a reliable indicator regarding the progression of clinical profile as well as the prognosis of the disease. A highly important cytokine, after the activated macrophages, is it. As a result, a measure for COVID-19 could be the control regarding systemic IL-6 levels in the individuals that have been infected by SARS-CoV-2. This study has demonstrated the significance of IL-6 in COVID-19's immunopathology
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spelling doaj.art-25f6f923b6f047f49a5d10a19d482ea92023-11-10T12:53:43ZengUniversity of Thi-Qarمجلة علوم ذي قار1991-86902709-02562023-06-0110110.32792/utq/utjsci/v10i1.895The role of Interleukin-6 (IL-6) in pathogensis of COVID -19Noorulhuda F. Khalaf0Sinai W. Mohammed1Ahmed Y. Hanoon2Tropical Biological Research Unit, College of Science/University of BaghdadUniversity of Baghdad, College of Science, Tropical Biological Research UnitTropical Biological Research Unit, College of Science/University of Baghdad Dissimilar to all other pandemics in the past five decades, the humanity has been ravaged by the coronavirus disease COVID-19. Starting from its outbreak, the disease's understanding has advanced quickly; multi-organ involvement is the key factor affecting the prognosis of the disease. Mortality and morbidity are closely related to acute respiratory distress syndrome, renal failure, cardiac failure, liver damage, multi-organ failure, and shock. In the initial phases of viral infection, detecting and controlling pro-inflammatory responses are essential. Throughout patient monitoring, it's crucial to consider the COVID-19 treatment's unknowable response. It has been discovered that IL-6 is causally linked to greater mortality. It is a reliable indicator regarding the progression of clinical profile as well as the prognosis of the disease. A highly important cytokine, after the activated macrophages, is it. As a result, a measure for COVID-19 could be the control regarding systemic IL-6 levels in the individuals that have been infected by SARS-CoV-2. This study has demonstrated the significance of IL-6 in COVID-19's immunopathology https://jsci.utq.edu.iq/index.php/main/article/view/895COVID-19, Cytokines, IL-6, Pathogenesis
spellingShingle Noorulhuda F. Khalaf
Sinai W. Mohammed
Ahmed Y. Hanoon
The role of Interleukin-6 (IL-6) in pathogensis of COVID -19
مجلة علوم ذي قار
COVID-19, Cytokines, IL-6, Pathogenesis
title The role of Interleukin-6 (IL-6) in pathogensis of COVID -19
title_full The role of Interleukin-6 (IL-6) in pathogensis of COVID -19
title_fullStr The role of Interleukin-6 (IL-6) in pathogensis of COVID -19
title_full_unstemmed The role of Interleukin-6 (IL-6) in pathogensis of COVID -19
title_short The role of Interleukin-6 (IL-6) in pathogensis of COVID -19
title_sort role of interleukin 6 il 6 in pathogensis of covid 19
topic COVID-19, Cytokines, IL-6, Pathogenesis
url https://jsci.utq.edu.iq/index.php/main/article/view/895
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