Bacterial Vaginosis Bacterial and Epithelial Cell Adhesion Molecules
Lactobacilli are member of normal vaginal flora. They maintain low pH of vaginal discharge by metabolising glycogen in vaginal epithelial cell and protects the vagina against the pathogenic microorganisms. However, the vaginal flora can be changed because of birth, taking antibiotics and contracepti...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Medical Network
2016-05-01
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| Series: | Gynecology Obstetrics & Reproductive Medicine |
| Subjects: | |
| Online Access: | http://gorm.com.tr/index.php/GORM/article/view/187 |
| _version_ | 1797908828268789760 |
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| author | Şayeste Demirezen Aydan Mutlu Sinan Beksaç |
| author_facet | Şayeste Demirezen Aydan Mutlu Sinan Beksaç |
| author_sort | Şayeste Demirezen |
| collection | DOAJ |
| description | Lactobacilli are member of normal vaginal flora. They maintain low pH of vaginal discharge by metabolising glycogen in vaginal epithelial cell and protects the vagina against the pathogenic microorganisms. However, the vaginal flora can be changed because of birth, taking antibiotics and contraceptive pills. Thus, whereas Lactobacilli population decreases, Gardnerella vaginalis and mixed anaerobic bacteria population increase and this situation causes an infection named Bacterial vaginosis. In this infection, the main diagnostic criteria are clue cells. The clue cell is a squamous epithelial cell which is covered by bacteria. First step of infection progress is adhesion of bacteria to epithelial cell through the adhesion
molecules. The most important adhesion molecules of epithelium are cadherins, fibronectins, Toll like receptors and carbohydrates. In bacteria, pilis, lypopolysaccaharide and biofilm have primary importance. In this review, the adhesion molecules are discussed in detail and their roles in formation of clue cell are clarified. |
| first_indexed | 2024-04-10T10:59:36Z |
| format | Article |
| id | doaj.art-25fa22d36a124652b630a6afb44383aa |
| institution | Directory Open Access Journal |
| issn | 1300-4751 |
| language | English |
| last_indexed | 2024-04-10T10:59:36Z |
| publishDate | 2016-05-01 |
| publisher | Medical Network |
| record_format | Article |
| series | Gynecology Obstetrics & Reproductive Medicine |
| spelling | doaj.art-25fa22d36a124652b630a6afb44383aa2023-02-15T16:19:46ZengMedical NetworkGynecology Obstetrics & Reproductive Medicine1300-47512016-05-01191126Bacterial Vaginosis Bacterial and Epithelial Cell Adhesion MoleculesŞayeste Demirezen0Aydan Mutlu1Sinan Beksaç2Hacettepe University, Faculty of Natural & Applied Science Department of Biology, AnkaraHacettepe University, Faculty of Natural & Applied Science Department of Biology, AnkaraHacettepe University, Faculty of Medicine, Department of Obstetrics and Gynecology, AnkaraLactobacilli are member of normal vaginal flora. They maintain low pH of vaginal discharge by metabolising glycogen in vaginal epithelial cell and protects the vagina against the pathogenic microorganisms. However, the vaginal flora can be changed because of birth, taking antibiotics and contraceptive pills. Thus, whereas Lactobacilli population decreases, Gardnerella vaginalis and mixed anaerobic bacteria population increase and this situation causes an infection named Bacterial vaginosis. In this infection, the main diagnostic criteria are clue cells. The clue cell is a squamous epithelial cell which is covered by bacteria. First step of infection progress is adhesion of bacteria to epithelial cell through the adhesion molecules. The most important adhesion molecules of epithelium are cadherins, fibronectins, Toll like receptors and carbohydrates. In bacteria, pilis, lypopolysaccaharide and biofilm have primary importance. In this review, the adhesion molecules are discussed in detail and their roles in formation of clue cell are clarified.http://gorm.com.tr/index.php/GORM/article/view/187Bacterial vaginosis, Clue cell, Cadherin, Pili, Biofilm |
| spellingShingle | Şayeste Demirezen Aydan Mutlu Sinan Beksaç Bacterial Vaginosis Bacterial and Epithelial Cell Adhesion Molecules Gynecology Obstetrics & Reproductive Medicine Bacterial vaginosis, Clue cell, Cadherin, Pili, Biofilm |
| title | Bacterial Vaginosis Bacterial and Epithelial Cell Adhesion Molecules |
| title_full | Bacterial Vaginosis Bacterial and Epithelial Cell Adhesion Molecules |
| title_fullStr | Bacterial Vaginosis Bacterial and Epithelial Cell Adhesion Molecules |
| title_full_unstemmed | Bacterial Vaginosis Bacterial and Epithelial Cell Adhesion Molecules |
| title_short | Bacterial Vaginosis Bacterial and Epithelial Cell Adhesion Molecules |
| title_sort | bacterial vaginosis bacterial and epithelial cell adhesion molecules |
| topic | Bacterial vaginosis, Clue cell, Cadherin, Pili, Biofilm |
| url | http://gorm.com.tr/index.php/GORM/article/view/187 |
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