Alzheimer Hastalığında Traskraniyal Manyetik Stimülasyon (TMS) Uygulamaları Üzerine Sistematik Bir Derleme
Alzheimer’s disease (AD), is characterized by its progressive feature and loss of cognitive functions, is common among dementia types. There is no curative treatment of the disease today. In recent years, transcranial magnetic stimulation (TMS) techniques together with drug therapy have been explore...
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| Format: | Article |
| Language: | English |
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Galenos Publishing House
2021-10-01
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| Series: | Bezmiâlem Science |
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| Online Access: |
http://bezmialemscience.org/archives/archive-detail/article-preview/alzheimer-hastalnda-traskraniyal-manyetik-stimlasy/47704
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| _version_ | 1797907551502729216 |
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| author | Halil Aziz VELİOĞLU Muhammed Yunus BEKTAY |
| author_facet | Halil Aziz VELİOĞLU Muhammed Yunus BEKTAY |
| author_sort | Halil Aziz VELİOĞLU |
| collection | DOAJ |
| description | Alzheimer’s disease (AD), is characterized by its progressive feature and loss of cognitive functions, is common among dementia types. There is no curative treatment of the disease today. In recent years, transcranial magnetic stimulation (TMS) techniques together with drug therapy have been explored by experts considering that they will produce beneficial results. Repetetive TMS (rTMS) can modulate cortical excitability and prevent long-term neuroplastic changes. The aim of this study is an updated and comprehensive systematic review of studies using TMS/rTMS in AD patients. Our study was designed as a systematic review prepared according to the PRISMA guideline. In this study, English and Turkish AD-TMS articles that entered the literature published between 2002 and 2017 were included. Randomized and non-randomized controlled clinical studies on humans evaluating the effectiveness of rTMS applications at different concentrations, durations and different regions in AD have been reviewed. The databases we used were Pubmed®, MEDLINE®, Webofscience®, EMBASE®, Türkiye Atif Dizini®. Keywords were “TMS, rTMS, Alzheimers Disease” used in our search, 116 artticles complied with the determined protocol were identified and 14 were included in our study. The studies presented in this review, show the therapeutic potential of rTMS in AD patients. Benefits of rTMS were to communicate with patients and especially caregivers in their daily activities, thereby improving their QoL. The possibility of using TMS to increase neuroplasticity is promising not only to improve our understanding of brain plasticity mechanisms, but also to design new neurorehabilitation strategies. |
| first_indexed | 2024-04-10T10:38:37Z |
| format | Article |
| id | doaj.art-25fa34480c874702b8ed4d01fab948e4 |
| institution | Directory Open Access Journal |
| issn | 2148-2373 |
| language | English |
| last_indexed | 2024-04-10T10:38:37Z |
| publishDate | 2021-10-01 |
| publisher | Galenos Publishing House |
| record_format | Article |
| series | Bezmiâlem Science |
| spelling | doaj.art-25fa34480c874702b8ed4d01fab948e42023-02-15T16:20:40ZengGalenos Publishing HouseBezmiâlem Science2148-23732021-10-019450351110.14235/bas.galenos.2020.438013049054Alzheimer Hastalığında Traskraniyal Manyetik Stimülasyon (TMS) Uygulamaları Üzerine Sistematik Bir DerlemeHalil Aziz VELİOĞLU0Muhammed Yunus BEKTAY1 Istanbul Medipol University, Health Sciences and Technology Research Institute (SABITA), Regenerative and Restorative Medicine Research Center (REMER), functional Imaging and Cognitive-Affective Neuroscience Lab (fINCAN), Istanbul, Turkey Bezmialem Vakıf University Faculty of Pharmacy, Department of Clinical Pharmacy, Istanbul, Turkey Alzheimer’s disease (AD), is characterized by its progressive feature and loss of cognitive functions, is common among dementia types. There is no curative treatment of the disease today. In recent years, transcranial magnetic stimulation (TMS) techniques together with drug therapy have been explored by experts considering that they will produce beneficial results. Repetetive TMS (rTMS) can modulate cortical excitability and prevent long-term neuroplastic changes. The aim of this study is an updated and comprehensive systematic review of studies using TMS/rTMS in AD patients. Our study was designed as a systematic review prepared according to the PRISMA guideline. In this study, English and Turkish AD-TMS articles that entered the literature published between 2002 and 2017 were included. Randomized and non-randomized controlled clinical studies on humans evaluating the effectiveness of rTMS applications at different concentrations, durations and different regions in AD have been reviewed. The databases we used were Pubmed®, MEDLINE®, Webofscience®, EMBASE®, Türkiye Atif Dizini®. Keywords were “TMS, rTMS, Alzheimers Disease” used in our search, 116 artticles complied with the determined protocol were identified and 14 were included in our study. The studies presented in this review, show the therapeutic potential of rTMS in AD patients. Benefits of rTMS were to communicate with patients and especially caregivers in their daily activities, thereby improving their QoL. The possibility of using TMS to increase neuroplasticity is promising not only to improve our understanding of brain plasticity mechanisms, but also to design new neurorehabilitation strategies. http://bezmialemscience.org/archives/archive-detail/article-preview/alzheimer-hastalnda-traskraniyal-manyetik-stimlasy/47704 alzheimer’s diseasedementiartms |
| spellingShingle | Halil Aziz VELİOĞLU Muhammed Yunus BEKTAY Alzheimer Hastalığında Traskraniyal Manyetik Stimülasyon (TMS) Uygulamaları Üzerine Sistematik Bir Derleme Bezmiâlem Science alzheimer’s disease dementia rtms |
| title | Alzheimer Hastalığında Traskraniyal Manyetik Stimülasyon (TMS) Uygulamaları Üzerine Sistematik Bir Derleme |
| title_full | Alzheimer Hastalığında Traskraniyal Manyetik Stimülasyon (TMS) Uygulamaları Üzerine Sistematik Bir Derleme |
| title_fullStr | Alzheimer Hastalığında Traskraniyal Manyetik Stimülasyon (TMS) Uygulamaları Üzerine Sistematik Bir Derleme |
| title_full_unstemmed | Alzheimer Hastalığında Traskraniyal Manyetik Stimülasyon (TMS) Uygulamaları Üzerine Sistematik Bir Derleme |
| title_short | Alzheimer Hastalığında Traskraniyal Manyetik Stimülasyon (TMS) Uygulamaları Üzerine Sistematik Bir Derleme |
| title_sort | alzheimer hastaliginda traskraniyal manyetik stimulasyon tms uygulamalari uzerine sistematik bir derleme |
| topic | alzheimer’s disease dementia rtms |
| url |
http://bezmialemscience.org/archives/archive-detail/article-preview/alzheimer-hastalnda-traskraniyal-manyetik-stimlasy/47704
|
| work_keys_str_mv | AT halilazizvelioglu alzheimerhastalıgındatraskraniyalmanyetikstimulasyontmsuygulamalarıuzerinesistematikbirderleme AT muhammedyunusbektay alzheimerhastalıgındatraskraniyalmanyetikstimulasyontmsuygulamalarıuzerinesistematikbirderleme |