Improved vaccine protection against retrovirus infection after co-administration of adenoviral vectors encoding viral antigens and type I interferon subtypes

Improved vaccine protection against retrovirus infection after co-administration of adenoviral vectors encoding viral antigens and type I interferon subtypes

<p>Abstract</p> <p>Background</p> <p>Type I interferons (IFNs) exhibit direct antiviral effects, but also distinct immunomodulatory properties. In this study, we analyzed type I IFN subtypes for their effect on prophylactic adenovirus-based anti-retroviral vaccination o...

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Bibliographic Details
Main Authors: Groitl Peter, Schimmer Simone, Nabi Ghulam, Tenbusch Matthias, Johrden Lena, Ontikatze Teona, Lietz Ruth, Bayer Wibke, Wolf Hans, Berry Cassandra M, Überla Klaus, Dittmer Ulf, Wildner Oliver
Format: Article
Language:English
Published: BMC 2011-09-01
Series:Retrovirology
Subjects:
Friend virus
interferon alpha subtypes
human adenovirus vectors
human immunodeficiency virus
vaccine
Online Access:http://www.retrovirology.com/content/8/1/75

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