Thymopentin promotes ovarian angiogenesis in mice by activating N6-methyladenosine (m6A) RNA modification of key factors in the Notch/Tie1 pathway

Thymopentin promotes ovarian angiogenesis in mice by activating N6-methyladenosine (m6A) RNA modification of key factors in the Notch/Tie1 pathway

Abstract: BACKGROUND: Premature ovarian failure (POF) is a typical condition of pathological ovarian ageing. Injuries and atrophies of blood vessels in the ovaries can lead to ovarian insufficiency, but the underlying mechanism remains unclear. AIMS: This study investigated the epigenetic mechanism...

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Bibliographic Details
Main Authors: Junjun Tao, Jiajia Lin, Xiaoli Nie, William Huang, Jianming Guo, Te Liu
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2019-01-01
Series:Vascular Investigation and Therapy
Subjects:
angiogenesis
notch/tie2 pathway
premature ovarian failure
rna n6-methyladenosine
thymopentin
Online Access:http://www.vitonline.org/article.asp?issn=2589-9686;year=2019;volume=2;issue=3;spage=63;epage=72;aulast=Tao

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