Retroperitoneal Sarcomas: An Update on the Diagnostic Pathology Approach
Retroperitoneal sarcomas are a heterogenous group of rare tumors arising in the retroperitoneum. Retroperitoneal sarcomas comprise approximately 10% of all soft tissue sarcomas. Though any soft tissue sarcoma histologic types may arise in the retroperitoneal space, liposarcoma (especially well-diffe...
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| Format: | Article |
| Language: | English |
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MDPI AG
2020-08-01
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| Series: | Diagnostics |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2075-4418/10/9/642 |
| _version_ | 1827707434534174720 |
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| author | Joon Hyuk Choi Jae Y. Ro |
| author_facet | Joon Hyuk Choi Jae Y. Ro |
| author_sort | Joon Hyuk Choi |
| collection | DOAJ |
| description | Retroperitoneal sarcomas are a heterogenous group of rare tumors arising in the retroperitoneum. Retroperitoneal sarcomas comprise approximately 10% of all soft tissue sarcomas. Though any soft tissue sarcoma histologic types may arise in the retroperitoneal space, liposarcoma (especially well-differentiated and dedifferentiated types) and leiomyosarcoma do so most commonly. Retroperitoneal sarcomas are diagnostically challenging, owing to their diversity and morphological overlap with other tumors arising in the retroperitoneum. An accurate diagnosis is necessary for correct management and prognostication. Herein, we provide an update on the diagnostic approach to retroperitoneal sarcomas and review their key histologic findings and differential diagnoses. |
| first_indexed | 2024-03-10T16:46:37Z |
| format | Article |
| id | doaj.art-2605bec79f9048f18e50a012f6e70801 |
| institution | Directory Open Access Journal |
| issn | 2075-4418 |
| language | English |
| last_indexed | 2024-03-10T16:46:37Z |
| publishDate | 2020-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Diagnostics |
| spelling | doaj.art-2605bec79f9048f18e50a012f6e708012023-11-20T11:33:06ZengMDPI AGDiagnostics2075-44182020-08-0110964210.3390/diagnostics10090642Retroperitoneal Sarcomas: An Update on the Diagnostic Pathology ApproachJoon Hyuk Choi0Jae Y. Ro1Department of Pathology, Yeungnam University College of Medicine, Daegu 42415, KoreaDepartment of Pathology and Genomic Medicine, Houston Methodist Hospital, Weill Medical College of Cornell University, Houston, TX 77030, USARetroperitoneal sarcomas are a heterogenous group of rare tumors arising in the retroperitoneum. Retroperitoneal sarcomas comprise approximately 10% of all soft tissue sarcomas. Though any soft tissue sarcoma histologic types may arise in the retroperitoneal space, liposarcoma (especially well-differentiated and dedifferentiated types) and leiomyosarcoma do so most commonly. Retroperitoneal sarcomas are diagnostically challenging, owing to their diversity and morphological overlap with other tumors arising in the retroperitoneum. An accurate diagnosis is necessary for correct management and prognostication. Herein, we provide an update on the diagnostic approach to retroperitoneal sarcomas and review their key histologic findings and differential diagnoses.https://www.mdpi.com/2075-4418/10/9/642retroperitoneal spacesarcomapathologyliposarcomaleiomyosarcoma |
| spellingShingle | Joon Hyuk Choi Jae Y. Ro Retroperitoneal Sarcomas: An Update on the Diagnostic Pathology Approach Diagnostics retroperitoneal space sarcoma pathology liposarcoma leiomyosarcoma |
| title | Retroperitoneal Sarcomas: An Update on the Diagnostic Pathology Approach |
| title_full | Retroperitoneal Sarcomas: An Update on the Diagnostic Pathology Approach |
| title_fullStr | Retroperitoneal Sarcomas: An Update on the Diagnostic Pathology Approach |
| title_full_unstemmed | Retroperitoneal Sarcomas: An Update on the Diagnostic Pathology Approach |
| title_short | Retroperitoneal Sarcomas: An Update on the Diagnostic Pathology Approach |
| title_sort | retroperitoneal sarcomas an update on the diagnostic pathology approach |
| topic | retroperitoneal space sarcoma pathology liposarcoma leiomyosarcoma |
| url | https://www.mdpi.com/2075-4418/10/9/642 |
| work_keys_str_mv | AT joonhyukchoi retroperitonealsarcomasanupdateonthediagnosticpathologyapproach AT jaeyro retroperitonealsarcomasanupdateonthediagnosticpathologyapproach |