Recent Progress on Urinary Exosomal miRNAs in Bladder Cancer
Bladder cancer (Bca) is one of the most common tumors in the urinary system. Cystoscopy biopsy is a gold standard for diagnosis of Bca in the clinic. However, cystoscopy biopsy is invasive, costly and invasive process causing pain in the patients. Because the Bca cells are closely in contact with ur...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Asian Medical Press Ltd.(H.K.)
2023-05-01
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| Series: | Annals of Urologic Oncology |
| Subjects: | |
| Online Access: | http://auo.asmepress.com/articles/new-98-265.html |
| _version_ | 1827937141194227712 |
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| author | Mohan Dong Kaiyuan Zhou |
| author_facet | Mohan Dong Kaiyuan Zhou |
| author_sort | Mohan Dong |
| collection | DOAJ |
| description | Bladder cancer (Bca) is one of the most common tumors in the urinary system. Cystoscopy biopsy is a gold standard for diagnosis of Bca in the clinic. However, cystoscopy biopsy is invasive, costly and invasive process causing pain in the patients. Because the Bca cells are closely in contact with urine, and the exosomes of the Bca can pass through the base membrane and transport the microRNA (miRNAs) to the urine, so the detection of the exosome-derived miRNAs in the urine is expected to be a new non-invasive method for diagnostics of Bca. Recently, liquid biopsy for miRNAs in urine is the recent research hotspot. In this review, we mainly introduce the feasibility of the application of the miRNAs from exosome to Bca, and its feasibility to detect Bca. |
| first_indexed | 2024-03-13T08:21:26Z |
| format | Article |
| id | doaj.art-26061004ed464f77a8f7316d2710e9a5 |
| institution | Directory Open Access Journal |
| issn | 2617-7765 2617-7773 |
| language | English |
| last_indexed | 2024-03-13T08:21:26Z |
| publishDate | 2023-05-01 |
| publisher | Asian Medical Press Ltd.(H.K.) |
| record_format | Article |
| series | Annals of Urologic Oncology |
| spelling | doaj.art-26061004ed464f77a8f7316d2710e9a52023-05-31T08:18:30ZengAsian Medical Press Ltd.(H.K.)Annals of Urologic Oncology2617-77652617-77732023-05-01610.32948/auo.2023.05.15Recent Progress on Urinary Exosomal miRNAs in Bladder CancerMohan Dong 0Kaiyuan Zhou1Medical Department, the First Affiliated Hospital, Air Force Medical University, Xi’an, China.Health Service Department, Air Force Medical University, Xi’an, China.Bladder cancer (Bca) is one of the most common tumors in the urinary system. Cystoscopy biopsy is a gold standard for diagnosis of Bca in the clinic. However, cystoscopy biopsy is invasive, costly and invasive process causing pain in the patients. Because the Bca cells are closely in contact with urine, and the exosomes of the Bca can pass through the base membrane and transport the microRNA (miRNAs) to the urine, so the detection of the exosome-derived miRNAs in the urine is expected to be a new non-invasive method for diagnostics of Bca. Recently, liquid biopsy for miRNAs in urine is the recent research hotspot. In this review, we mainly introduce the feasibility of the application of the miRNAs from exosome to Bca, and its feasibility to detect Bca.http://auo.asmepress.com/articles/new-98-265.htmlexosomal mirnasurinebladder cancerdiagnostics |
| spellingShingle | Mohan Dong Kaiyuan Zhou Recent Progress on Urinary Exosomal miRNAs in Bladder Cancer Annals of Urologic Oncology exosomal mirnas urine bladder cancer diagnostics |
| title | Recent Progress on Urinary Exosomal miRNAs in Bladder Cancer |
| title_full | Recent Progress on Urinary Exosomal miRNAs in Bladder Cancer |
| title_fullStr | Recent Progress on Urinary Exosomal miRNAs in Bladder Cancer |
| title_full_unstemmed | Recent Progress on Urinary Exosomal miRNAs in Bladder Cancer |
| title_short | Recent Progress on Urinary Exosomal miRNAs in Bladder Cancer |
| title_sort | recent progress on urinary exosomal mirnas in bladder cancer |
| topic | exosomal mirnas urine bladder cancer diagnostics |
| url | http://auo.asmepress.com/articles/new-98-265.html |
| work_keys_str_mv | AT mohandong recentprogressonurinaryexosomalmirnasinbladdercancer AT kaiyuanzhou recentprogressonurinaryexosomalmirnasinbladdercancer |