A Randomized, Prospective Evaluation the Effect of Oral Pregabalin in Forearm Surgery with Infraclavicular Nerve Block
Introduction:The infraclavicular block method has been increasingly used in hand, wrist, and forearm surgery in anesthesia practice. Although the infraclavicular block method provides appropriate postoperative analgesic effect, patients still suffer from postoperative pain at high rates. Opioids are...
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| Format: | Article |
| Language: | English |
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Galenos Yayinevi
2023-02-01
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| Series: | İstanbul Medical Journal |
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| Online Access: |
http://istanbulmedicaljournal.org/archives/archive-detail/article-preview/a-randomized-prospective-evaluation-the-effect-of-/58695
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| _version_ | 1797894312493580288 |
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| author | Özlem Deligöz |
| author_facet | Özlem Deligöz |
| author_sort | Özlem Deligöz |
| collection | DOAJ |
| description | Introduction:The infraclavicular block method has been increasingly used in hand, wrist, and forearm surgery in anesthesia practice. Although the infraclavicular block method provides appropriate postoperative analgesic effect, patients still suffer from postoperative pain at high rates. Opioids are widely used for postoperative analgesia. There are many studies showings that taking oral pregabalin before the operation reduces postoperative pain and opioid use. In this study, we investigated the effect of preoperative use of 150 mg oral pregabalin on infraclavicular sensory block duration and opioid use.Methods:Ethics committee approval and patient consents were obtained for the study. The study included 60 patients between the ages of 18 and 65 who would undergo an American Society of Anesthesiologists I-II hand, wrist or forearm surgery. The control group (group K) did not take medication before the operation. The pregabalin group (group P) took 150 mg of oral pregabalin an hour before the operation. Ultrasound-guided infraclavicular block was applied to both groups. Patients were observed for 24 hours per operatively and postoperatively in terms of analgesic medication needs and complications.Results:Postoperative analgesic use was observed to be higher in group K (p<0.05). There was no significant difference in sensory block and motor block initial durations in group K and group P (p>0.05). However, the sensory block completion time was statistically significantly longer in group P than in group K (p<0.05). There was no statistically significant difference between the motor block ending times of both study groups in terms of side effects (p>0.05).Conclusion:In this study, we concluded that a single dose of 150 mg oral pregabalin treatment applied before the operation prolongs the infraclavicular sensory block duration and reduces the need for analgesic drugs in the first 24 hours postoperatively. |
| first_indexed | 2024-04-10T07:06:56Z |
| format | Article |
| id | doaj.art-26109b70a2d24d67954987e9b0ac8641 |
| institution | Directory Open Access Journal |
| issn | 2619-9793 2148-094X |
| language | English |
| last_indexed | 2024-04-10T07:06:56Z |
| publishDate | 2023-02-01 |
| publisher | Galenos Yayinevi |
| record_format | Article |
| series | İstanbul Medical Journal |
| spelling | doaj.art-26109b70a2d24d67954987e9b0ac86412023-02-27T05:59:15ZengGalenos Yayineviİstanbul Medical Journal2619-97932148-094X2023-02-01241838710.4274/imj.galenos.2023.3753113049054A Randomized, Prospective Evaluation the Effect of Oral Pregabalin in Forearm Surgery with Infraclavicular Nerve BlockÖzlem Deligöz0 University of Health Sciences Turkey, Haydarpaşa Numune Training and Research Hospital, Clinic of Anesthesiology and Reanimation, İstanbul, Turkey Introduction:The infraclavicular block method has been increasingly used in hand, wrist, and forearm surgery in anesthesia practice. Although the infraclavicular block method provides appropriate postoperative analgesic effect, patients still suffer from postoperative pain at high rates. Opioids are widely used for postoperative analgesia. There are many studies showings that taking oral pregabalin before the operation reduces postoperative pain and opioid use. In this study, we investigated the effect of preoperative use of 150 mg oral pregabalin on infraclavicular sensory block duration and opioid use.Methods:Ethics committee approval and patient consents were obtained for the study. The study included 60 patients between the ages of 18 and 65 who would undergo an American Society of Anesthesiologists I-II hand, wrist or forearm surgery. The control group (group K) did not take medication before the operation. The pregabalin group (group P) took 150 mg of oral pregabalin an hour before the operation. Ultrasound-guided infraclavicular block was applied to both groups. Patients were observed for 24 hours per operatively and postoperatively in terms of analgesic medication needs and complications.Results:Postoperative analgesic use was observed to be higher in group K (p<0.05). There was no significant difference in sensory block and motor block initial durations in group K and group P (p>0.05). However, the sensory block completion time was statistically significantly longer in group P than in group K (p<0.05). There was no statistically significant difference between the motor block ending times of both study groups in terms of side effects (p>0.05).Conclusion:In this study, we concluded that a single dose of 150 mg oral pregabalin treatment applied before the operation prolongs the infraclavicular sensory block duration and reduces the need for analgesic drugs in the first 24 hours postoperatively. http://istanbulmedicaljournal.org/archives/archive-detail/article-preview/a-randomized-prospective-evaluation-the-effect-of-/58695 infraclavicular blockpregalabalinpostoperative analgesia |
| spellingShingle | Özlem Deligöz A Randomized, Prospective Evaluation the Effect of Oral Pregabalin in Forearm Surgery with Infraclavicular Nerve Block İstanbul Medical Journal infraclavicular block pregalabalin postoperative analgesia |
| title | A Randomized, Prospective Evaluation the Effect of Oral Pregabalin in Forearm Surgery with Infraclavicular Nerve Block |
| title_full | A Randomized, Prospective Evaluation the Effect of Oral Pregabalin in Forearm Surgery with Infraclavicular Nerve Block |
| title_fullStr | A Randomized, Prospective Evaluation the Effect of Oral Pregabalin in Forearm Surgery with Infraclavicular Nerve Block |
| title_full_unstemmed | A Randomized, Prospective Evaluation the Effect of Oral Pregabalin in Forearm Surgery with Infraclavicular Nerve Block |
| title_short | A Randomized, Prospective Evaluation the Effect of Oral Pregabalin in Forearm Surgery with Infraclavicular Nerve Block |
| title_sort | randomized prospective evaluation the effect of oral pregabalin in forearm surgery with infraclavicular nerve block |
| topic | infraclavicular block pregalabalin postoperative analgesia |
| url |
http://istanbulmedicaljournal.org/archives/archive-detail/article-preview/a-randomized-prospective-evaluation-the-effect-of-/58695
|
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