Sex differences in colonic gene expression and fecal microbiota composition in a mouse model of obesity-associated colorectal cancer

Abstract This study investigated the sex-specific correlation between obesity and colorectal cancer emphasizing a more pronounced association in males. Estrogen, chromosomal genes, and gut bacteria were assessed in C57BL6/J male, female and ovariectomized (OVX) female mice, subjected to either a low...

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Bibliographic Details
Main Authors: Yoo-Mee Chang, Yoo-Ree Kang, Yu-Gyeong Lee, Mi-Kyung Sung
Format: Article
Language:English
Published: Nature Portfolio 2024-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-024-53861-z