Abnormal Uterine Bleeding Associated with Bupropion: A Case Report
In the literature, many cases of abnormal uterine bleeding associated with selective serotonin reuptake inhibitors have been reported as a side effect of antidepressant treatment. However, abnormal uterine bleeding associated with bupropion, a norepinephrine-dopamine reuptake inhibitor, has been rep...
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| Format: | Article |
| Language: | English |
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Galenos Yayinevi
2022-09-01
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| Series: | Bagcilar Medical Bulletin |
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| Online Access: |
http://behmedicalbulletin.org/archives/archive-detail/article-preview/abnormal-uterine-bleeding-associated-with-bupropio/52862
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| _version_ | 1828025643591270400 |
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| author | Melek Kanarya Vardar Evrim Ebru Kovalak |
| author_facet | Melek Kanarya Vardar Evrim Ebru Kovalak |
| author_sort | Melek Kanarya Vardar |
| collection | DOAJ |
| description | In the literature, many cases of abnormal uterine bleeding associated with selective serotonin reuptake inhibitors have been reported as a side effect of antidepressant treatment. However, abnormal uterine bleeding associated with bupropion, a norepinephrine-dopamine reuptake inhibitor, has been reported in only two case studies to date. A 28-year-old, oligomenorrheic female patient was admitted to the psychiatry department with the symptoms of depression. The patient was diagnosed with major depression and bupropion 150 mg/day was prescribed. After the initiation of the treatment, the patient experienced mild-to-moderate uterine bleeding, which was resolved with the discontinuation of the drug. In the patient’s anamnesis, it was learned that the same side effect had developed with the previous bupropion treatment. A comprehensive examination of the patient suggested that this adverse effect could strongly be associated with bupropion. This case supports the view that antidepressants can cause bleeding abnormalities, in particular vaginal bleeding caused by bupropion usage. Physicians who prescribe bupropion should carefully follow up their patients to identify such adverse effects. |
| first_indexed | 2024-04-10T13:04:37Z |
| format | Article |
| id | doaj.art-2622967e4c0541f39d5b55a0641ad513 |
| institution | Directory Open Access Journal |
| issn | 2547-9431 |
| language | English |
| last_indexed | 2024-04-10T13:04:37Z |
| publishDate | 2022-09-01 |
| publisher | Galenos Yayinevi |
| record_format | Article |
| series | Bagcilar Medical Bulletin |
| spelling | doaj.art-2622967e4c0541f39d5b55a0641ad5132023-02-15T16:12:59ZengGalenos YayineviBagcilar Medical Bulletin2547-94312022-09-017328829010.4274/BMB.galenos.2022.2022-06-06113049054Abnormal Uterine Bleeding Associated with Bupropion: A Case ReportMelek Kanarya Vardar0Evrim Ebru Kovalak1 University of Health Sciences Turkey, İstanbul Bağcılar Traning and Research Hospital, Clinic of Psychiatry, İstanbul, Turkey University of Health Sciences Turkey, İstanbul Bağcılar Traning and Research Hospital, Clinic of Obstetrics and Gynecology, İstanbul, Turkey In the literature, many cases of abnormal uterine bleeding associated with selective serotonin reuptake inhibitors have been reported as a side effect of antidepressant treatment. However, abnormal uterine bleeding associated with bupropion, a norepinephrine-dopamine reuptake inhibitor, has been reported in only two case studies to date. A 28-year-old, oligomenorrheic female patient was admitted to the psychiatry department with the symptoms of depression. The patient was diagnosed with major depression and bupropion 150 mg/day was prescribed. After the initiation of the treatment, the patient experienced mild-to-moderate uterine bleeding, which was resolved with the discontinuation of the drug. In the patient’s anamnesis, it was learned that the same side effect had developed with the previous bupropion treatment. A comprehensive examination of the patient suggested that this adverse effect could strongly be associated with bupropion. This case supports the view that antidepressants can cause bleeding abnormalities, in particular vaginal bleeding caused by bupropion usage. Physicians who prescribe bupropion should carefully follow up their patients to identify such adverse effects. http://behmedicalbulletin.org/archives/archive-detail/article-preview/abnormal-uterine-bleeding-associated-with-bupropio/52862 abnormal uterine bleedingadverse effectbupropioncase reports |
| spellingShingle | Melek Kanarya Vardar Evrim Ebru Kovalak Abnormal Uterine Bleeding Associated with Bupropion: A Case Report Bagcilar Medical Bulletin abnormal uterine bleeding adverse effect bupropion case reports |
| title | Abnormal Uterine Bleeding Associated with Bupropion: A Case Report |
| title_full | Abnormal Uterine Bleeding Associated with Bupropion: A Case Report |
| title_fullStr | Abnormal Uterine Bleeding Associated with Bupropion: A Case Report |
| title_full_unstemmed | Abnormal Uterine Bleeding Associated with Bupropion: A Case Report |
| title_short | Abnormal Uterine Bleeding Associated with Bupropion: A Case Report |
| title_sort | abnormal uterine bleeding associated with bupropion a case report |
| topic | abnormal uterine bleeding adverse effect bupropion case reports |
| url |
http://behmedicalbulletin.org/archives/archive-detail/article-preview/abnormal-uterine-bleeding-associated-with-bupropio/52862
|
| work_keys_str_mv | AT melekkanaryavardar abnormaluterinebleedingassociatedwithbupropionacasereport AT evrimebrukovalak abnormaluterinebleedingassociatedwithbupropionacasereport |