Cloning of the repertoire of individual Plasmodium falciparum var genes using transformation associated recombination (TAR).

Cloning of the repertoire of individual Plasmodium falciparum var genes using transformation associated recombination (TAR).

One of the major virulence factors of the malaria causing parasite is the Plasmodium falciparum encoded erythrocyte membrane protein 1 (PfEMP1). It is translocated to It the membrane of infected erythrocytes and expressed from approximately 60 var genes in a mutually exclusive manner. Switching of v...

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Bibliographic Details
Main Authors: Annette Gaida, Marion M Becker, Christoph D Schmid, Tobias Bühlmann, Edward J Louis, Hans-Peter Beck
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-03-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3049791?pdf=render

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