Medication-Related Hospital Admissions and Emergency Department Visits in Older People with Diabetes: A Systematic Review
Limited data are available regarding adverse drug reactions (ADRs) and medication-related hospitalisations or emergency department (ED) visits in older adults with diabetes, especially since the emergence of newer antidiabetic agents. This systematic review aimed to explore the nature of hospital ad...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2024-01-01
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| Series: | Journal of Clinical Medicine |
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| Online Access: | https://www.mdpi.com/2077-0383/13/2/530 |
| _version_ | 1797339664541024256 |
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| author | Azizah Vonna Mohammed S. Salahudeen Gregory M. Peterson |
| author_facet | Azizah Vonna Mohammed S. Salahudeen Gregory M. Peterson |
| author_sort | Azizah Vonna |
| collection | DOAJ |
| description | Limited data are available regarding adverse drug reactions (ADRs) and medication-related hospitalisations or emergency department (ED) visits in older adults with diabetes, especially since the emergence of newer antidiabetic agents. This systematic review aimed to explore the nature of hospital admissions and ED visits that are medication-related in older adults with diabetes. The review was conducted according to the PRISMA guidelines. Studies in English that reported on older adults (mean age ≥ 60 years) with diabetes admitted to the hospital or presenting to ED due to medication-related problems and published between January 2000 and October 2023 were identified using Medline, Embase, and International Pharmaceutical Abstracts databases. Thirty-five studies were included. Medication-related hospital admissions and ED visits were all reported as episodes of hypoglycaemia and were most frequently associated with insulins and sulfonylureas. The studies indicated a decline in hypoglycaemia-related hospitalisations or ED presentations in older adults with diabetes since 2015. However, the associated medications remain the same. This finding suggests that older patients on insulin or secretagogue agents should be closely monitored to prevent potential adverse events, and newer agents should be used whenever clinically appropriate. |
| first_indexed | 2024-03-08T09:51:39Z |
| format | Article |
| id | doaj.art-26286ada88a64998996dfb74dc8da81d |
| institution | Directory Open Access Journal |
| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-03-08T09:51:39Z |
| publishDate | 2024-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Clinical Medicine |
| spelling | doaj.art-26286ada88a64998996dfb74dc8da81d2024-01-29T14:02:42ZengMDPI AGJournal of Clinical Medicine2077-03832024-01-0113253010.3390/jcm13020530Medication-Related Hospital Admissions and Emergency Department Visits in Older People with Diabetes: A Systematic ReviewAzizah Vonna0Mohammed S. Salahudeen1Gregory M. Peterson2School of Pharmacy and Pharmacology, College of Health and Medicine, University of Tasmania, Hobart 7005, AustraliaSchool of Pharmacy and Pharmacology, College of Health and Medicine, University of Tasmania, Hobart 7005, AustraliaSchool of Pharmacy and Pharmacology, College of Health and Medicine, University of Tasmania, Hobart 7005, AustraliaLimited data are available regarding adverse drug reactions (ADRs) and medication-related hospitalisations or emergency department (ED) visits in older adults with diabetes, especially since the emergence of newer antidiabetic agents. This systematic review aimed to explore the nature of hospital admissions and ED visits that are medication-related in older adults with diabetes. The review was conducted according to the PRISMA guidelines. Studies in English that reported on older adults (mean age ≥ 60 years) with diabetes admitted to the hospital or presenting to ED due to medication-related problems and published between January 2000 and October 2023 were identified using Medline, Embase, and International Pharmaceutical Abstracts databases. Thirty-five studies were included. Medication-related hospital admissions and ED visits were all reported as episodes of hypoglycaemia and were most frequently associated with insulins and sulfonylureas. The studies indicated a decline in hypoglycaemia-related hospitalisations or ED presentations in older adults with diabetes since 2015. However, the associated medications remain the same. This finding suggests that older patients on insulin or secretagogue agents should be closely monitored to prevent potential adverse events, and newer agents should be used whenever clinically appropriate.https://www.mdpi.com/2077-0383/13/2/530medication-related problemsadverse drug reactionhospital admissionemergency department visitdiabetes mellitusolder people |
| spellingShingle | Azizah Vonna Mohammed S. Salahudeen Gregory M. Peterson Medication-Related Hospital Admissions and Emergency Department Visits in Older People with Diabetes: A Systematic Review Journal of Clinical Medicine medication-related problems adverse drug reaction hospital admission emergency department visit diabetes mellitus older people |
| title | Medication-Related Hospital Admissions and Emergency Department Visits in Older People with Diabetes: A Systematic Review |
| title_full | Medication-Related Hospital Admissions and Emergency Department Visits in Older People with Diabetes: A Systematic Review |
| title_fullStr | Medication-Related Hospital Admissions and Emergency Department Visits in Older People with Diabetes: A Systematic Review |
| title_full_unstemmed | Medication-Related Hospital Admissions and Emergency Department Visits in Older People with Diabetes: A Systematic Review |
| title_short | Medication-Related Hospital Admissions and Emergency Department Visits in Older People with Diabetes: A Systematic Review |
| title_sort | medication related hospital admissions and emergency department visits in older people with diabetes a systematic review |
| topic | medication-related problems adverse drug reaction hospital admission emergency department visit diabetes mellitus older people |
| url | https://www.mdpi.com/2077-0383/13/2/530 |
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