TWEAK/Fn14 Is Overexpressed in Crohn’s Disease and Mediates Experimental Ileitis by Regulating Critical Innate and Adaptive Immune PathwaysSummary
Background & Aims: Crohn’s disease (CD) is a debilitating inflammatory disorder that affects more than 1.6 million people in North America alone. Members of the tumor necrosis factor superfamily are key regulators of intestinal inflammation; specifically, tumor necrosis factor–like weak inducer...
Main Authors: | Luca Di Martino, Abdullah Osme, Sarah Kossak-Gupta, Theresa T. Pizarro, Fabio Cominelli |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2019-01-01
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Series: | Cellular and Molecular Gastroenterology and Hepatology |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2352345X19300712 |
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