Paeoniflorin in Paeoniaceae: Distribution, influencing factors, and biosynthesis
Paeoniflorin, a monoterpene glucoside, is increasingly used in the clinical treatment of many diseases because it has a variety of pharmacological activities. Besides, paeoniflorin has been considered the characteristic chemical constituent of Paeoniaceae plants since it was first reported in 1963....
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-09-01
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| Series: | Frontiers in Plant Science |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fpls.2022.980854/full |
| _version_ | 1817995102788780032 |
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| author | Xiao-Xiao Zhang Xiao-Xiao Zhang Jia-Qi Zuo Yi-Ting Wang Hui-Yun Duan Jun-Hui Yuan Yong-Hong Hu |
| author_facet | Xiao-Xiao Zhang Xiao-Xiao Zhang Jia-Qi Zuo Yi-Ting Wang Hui-Yun Duan Jun-Hui Yuan Yong-Hong Hu |
| author_sort | Xiao-Xiao Zhang |
| collection | DOAJ |
| description | Paeoniflorin, a monoterpene glucoside, is increasingly used in the clinical treatment of many diseases because it has a variety of pharmacological activities. Besides, paeoniflorin has been considered the characteristic chemical constituent of Paeoniaceae plants since it was first reported in 1963. Therefore, how to better develop and utilize paeoniflorin in Paeoniaceae has always been a research hotspot. We reviewed the current knowledge on paeoniflorin in Paeoniaceae, with particular emphasis on its distribution and influencing factors. Moreover, the limited understanding of the biosynthesis pathway has restricted the production of paeoniflorin by synthetic biology. This review provides insights into the post-modification pathway of paeoniflorin biosynthesis and proposes directions for further analysis in the future. |
| first_indexed | 2024-04-14T02:01:07Z |
| format | Article |
| id | doaj.art-262f327ae95c4fd3a9a4a1f3b3b974f5 |
| institution | Directory Open Access Journal |
| issn | 1664-462X |
| language | English |
| last_indexed | 2024-04-14T02:01:07Z |
| publishDate | 2022-09-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Plant Science |
| spelling | doaj.art-262f327ae95c4fd3a9a4a1f3b3b974f52022-12-22T02:18:50ZengFrontiers Media S.A.Frontiers in Plant Science1664-462X2022-09-011310.3389/fpls.2022.980854980854Paeoniflorin in Paeoniaceae: Distribution, influencing factors, and biosynthesisXiao-Xiao Zhang0Xiao-Xiao Zhang1Jia-Qi Zuo2Yi-Ting Wang3Hui-Yun Duan4Jun-Hui Yuan5Yong-Hong Hu6College of Landscape Architecture and Arts, Northwest A&F University, Yangling, Shaanxi, ChinaShanghai Key Laboratory of Plant Functional Genomics and Resources, Shanghai Chenshan Botanical Garden, Shanghai, ChinaCollege of Landscape Architecture and Arts, Northwest A&F University, Yangling, Shaanxi, ChinaCollege of Landscape Architecture and Arts, Northwest A&F University, Yangling, Shaanxi, ChinaCollege of Landscape Architecture and Arts, Northwest A&F University, Yangling, Shaanxi, ChinaShanghai Key Laboratory of Plant Functional Genomics and Resources, Shanghai Chenshan Botanical Garden, Shanghai, ChinaShanghai Key Laboratory of Plant Functional Genomics and Resources, Shanghai Chenshan Botanical Garden, Shanghai, ChinaPaeoniflorin, a monoterpene glucoside, is increasingly used in the clinical treatment of many diseases because it has a variety of pharmacological activities. Besides, paeoniflorin has been considered the characteristic chemical constituent of Paeoniaceae plants since it was first reported in 1963. Therefore, how to better develop and utilize paeoniflorin in Paeoniaceae has always been a research hotspot. We reviewed the current knowledge on paeoniflorin in Paeoniaceae, with particular emphasis on its distribution and influencing factors. Moreover, the limited understanding of the biosynthesis pathway has restricted the production of paeoniflorin by synthetic biology. This review provides insights into the post-modification pathway of paeoniflorin biosynthesis and proposes directions for further analysis in the future.https://www.frontiersin.org/articles/10.3389/fpls.2022.980854/fullPaeoniaceaePaeoniflorininfluencing factorsbiosynthesispost-modification enzymeMonoterpene |
| spellingShingle | Xiao-Xiao Zhang Xiao-Xiao Zhang Jia-Qi Zuo Yi-Ting Wang Hui-Yun Duan Jun-Hui Yuan Yong-Hong Hu Paeoniflorin in Paeoniaceae: Distribution, influencing factors, and biosynthesis Frontiers in Plant Science Paeoniaceae Paeoniflorin influencing factors biosynthesis post-modification enzyme Monoterpene |
| title | Paeoniflorin in Paeoniaceae: Distribution, influencing factors, and biosynthesis |
| title_full | Paeoniflorin in Paeoniaceae: Distribution, influencing factors, and biosynthesis |
| title_fullStr | Paeoniflorin in Paeoniaceae: Distribution, influencing factors, and biosynthesis |
| title_full_unstemmed | Paeoniflorin in Paeoniaceae: Distribution, influencing factors, and biosynthesis |
| title_short | Paeoniflorin in Paeoniaceae: Distribution, influencing factors, and biosynthesis |
| title_sort | paeoniflorin in paeoniaceae distribution influencing factors and biosynthesis |
| topic | Paeoniaceae Paeoniflorin influencing factors biosynthesis post-modification enzyme Monoterpene |
| url | https://www.frontiersin.org/articles/10.3389/fpls.2022.980854/full |
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