Smartphone camera oximetry in an induced hypoxemia study

Abstract Hypoxemia, a medical condition that occurs when the blood is not carrying enough oxygen to adequately supply the tissues, is a leading indicator for dangerous complications of respiratory diseases like asthma, COPD, and COVID-19. While purpose-built pulse oximeters can provide accurate bloo...

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Main Authors: Jason S. Hoffman, Varun K. Viswanath, Caiwei Tian, Xinyi Ding, Matthew J. Thompson, Eric C. Larson, Shwetak N. Patel, Edward J. Wang
Format: Article
Language:English
Published: Nature Portfolio 2022-09-01
Series:npj Digital Medicine
Online Access:https://doi.org/10.1038/s41746-022-00665-y
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author Jason S. Hoffman
Varun K. Viswanath
Caiwei Tian
Xinyi Ding
Matthew J. Thompson
Eric C. Larson
Shwetak N. Patel
Edward J. Wang
author_facet Jason S. Hoffman
Varun K. Viswanath
Caiwei Tian
Xinyi Ding
Matthew J. Thompson
Eric C. Larson
Shwetak N. Patel
Edward J. Wang
author_sort Jason S. Hoffman
collection DOAJ
description Abstract Hypoxemia, a medical condition that occurs when the blood is not carrying enough oxygen to adequately supply the tissues, is a leading indicator for dangerous complications of respiratory diseases like asthma, COPD, and COVID-19. While purpose-built pulse oximeters can provide accurate blood-oxygen saturation (SpO2) readings that allow for diagnosis of hypoxemia, enabling this capability in unmodified smartphone cameras via a software update could give more people access to important information about their health. Towards this goal, we performed the first clinical development validation on a smartphone camera-based SpO2 sensing system using a varied fraction of inspired oxygen (FiO2) protocol, creating a clinically relevant validation dataset for solely smartphone-based contact PPG methods on a wider range of SpO2 values (70–100%) than prior studies (85–100%). We built a deep learning model using this data to demonstrate an overall MAE = 5.00% SpO2 while identifying positive cases of low SpO2 < 90% with 81% sensitivity and 79% specificity. We also provide the data in open-source format, so that others may build on this work.
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spelling doaj.art-2637ce72ffd3438193df03560ee8fbeb2023-11-02T05:20:54ZengNature Portfolionpj Digital Medicine2398-63522022-09-015111010.1038/s41746-022-00665-ySmartphone camera oximetry in an induced hypoxemia studyJason S. Hoffman0Varun K. Viswanath1Caiwei Tian2Xinyi Ding3Matthew J. Thompson4Eric C. Larson5Shwetak N. Patel6Edward J. Wang7Paul G. Allen School of Computer Science and Engineering, University of WashingtonDepartment of Electrical and Computer Engineering, University of California San DiegoPaul G. Allen School of Computer Science and Engineering, University of WashingtonDepartment of Computer Science, Southern Methodist UniversityDepartment of Family Medicine, University of WashingtonDepartment of Computer Science, Southern Methodist UniversityPaul G. Allen School of Computer Science and Engineering, University of WashingtonDepartment of Electrical and Computer Engineering, University of California San DiegoAbstract Hypoxemia, a medical condition that occurs when the blood is not carrying enough oxygen to adequately supply the tissues, is a leading indicator for dangerous complications of respiratory diseases like asthma, COPD, and COVID-19. While purpose-built pulse oximeters can provide accurate blood-oxygen saturation (SpO2) readings that allow for diagnosis of hypoxemia, enabling this capability in unmodified smartphone cameras via a software update could give more people access to important information about their health. Towards this goal, we performed the first clinical development validation on a smartphone camera-based SpO2 sensing system using a varied fraction of inspired oxygen (FiO2) protocol, creating a clinically relevant validation dataset for solely smartphone-based contact PPG methods on a wider range of SpO2 values (70–100%) than prior studies (85–100%). We built a deep learning model using this data to demonstrate an overall MAE = 5.00% SpO2 while identifying positive cases of low SpO2 < 90% with 81% sensitivity and 79% specificity. We also provide the data in open-source format, so that others may build on this work.https://doi.org/10.1038/s41746-022-00665-y
spellingShingle Jason S. Hoffman
Varun K. Viswanath
Caiwei Tian
Xinyi Ding
Matthew J. Thompson
Eric C. Larson
Shwetak N. Patel
Edward J. Wang
Smartphone camera oximetry in an induced hypoxemia study
npj Digital Medicine
title Smartphone camera oximetry in an induced hypoxemia study
title_full Smartphone camera oximetry in an induced hypoxemia study
title_fullStr Smartphone camera oximetry in an induced hypoxemia study
title_full_unstemmed Smartphone camera oximetry in an induced hypoxemia study
title_short Smartphone camera oximetry in an induced hypoxemia study
title_sort smartphone camera oximetry in an induced hypoxemia study
url https://doi.org/10.1038/s41746-022-00665-y
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