Detection of Tumor DNA in Bronchoscopic Fluids in Peripheral NSCLC: A Proof-of-Concept Study

Detection of Tumor DNA in Bronchoscopic Fluids in Peripheral NSCLC: A Proof-of-Concept Study

Introduction: DNA genotyping from plasma is a useful tool for molecular characterization of NSCLC. Nevertheless, the false-negative rate justifies the development of methods with higher sensitivity, especially in difficult-to-reach peripheral lung tumors. Methods: We aimed at comparing molecular ana...

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Main Authors: Gwenaëlle Arhant, MD, Samy Lachkar, MD, Pierre-Alain Thiebaut, MD, PhD, Florent Marguet, MD, PhD, Aude Lamy, PhD, Luc Thiberville, MD, PhD, Mathieu Salaün, MD, PhD, Florian Guisier, MD, PhD, Jean-Christophe Sabourin, MD, PhD, Nicolas Piton, MD, PhD
Format: Article
Language:English
Published: Elsevier 2024-02-01
Series:JTO Clinical and Research Reports
Subjects:
Liquid biopsy
Tumor genotyping
Non–small cell lung carcinoma
Peripheral lung nodule
Radial-EndoBronchial UltraSound
Targeted therapy
Online Access:http://www.sciencedirect.com/science/article/pii/S266636432300139X

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