Epileptic Seizure: An Atypical Presentation in Brucellosis
Neurologic involvement occurs in approximately 10% cases of brucellosis and is a serious complication. It manifests with unique and some rare manifestations. We present the first patient with seizures in Brucella meningitis without encephalitis, space-occupying lesion, or vascular involvement. The p...
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| Format: | Article |
| Language: | English |
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Tehran University of Medical Sciences
2017-01-01
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| Series: | Case Reports in Clinical Practice |
| Subjects: | |
| Online Access: | https://crcp.tums.ac.ir/index.php/crcp/article/view/70 |
| _version_ | 1828766836976517120 |
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| author | Simin-Dokht Shoaei Mohamad Farahbakhsh Mehrdad Haghighi Fahime Hadavand |
| author_facet | Simin-Dokht Shoaei Mohamad Farahbakhsh Mehrdad Haghighi Fahime Hadavand |
| author_sort | Simin-Dokht Shoaei |
| collection | DOAJ |
| description | Neurologic involvement occurs in approximately 10% cases of brucellosis and is a serious complication. It manifests with unique and some rare manifestations. We present the first patient with seizures in Brucella meningitis without encephalitis, space-occupying lesion, or vascular involvement. The patient is a 23-year-old man with complaint of seizure. He had generalized weakness for 2 weeks before. In 1st day of admission, he had the second convulsion. Cerebrospinal fluid (CSF) on admission showed lymphocytic pleocytosis and high protein. Brain magnetic resonance imaging and computed tomography scan were normal. Further evaluations resulted a positive Wright, Coombs’ Wright, and 2- mercaptoethanol (2ME) tests. Specific regimen with rifampin, doxycycline, and ceftriaxone in the 1st month then the first two with trimethoprimsulfamethoxazole (TMP-SMX) for 5 months administered. 6 months after completion of treatment in follow-up he has no seizure, systemic or localized symptoms. |
| first_indexed | 2024-12-11T07:14:32Z |
| format | Article |
| id | doaj.art-26400a5acd4b45f1b295d027b5d98a5d |
| institution | Directory Open Access Journal |
| issn | 2538-2683 2538-2691 |
| language | English |
| last_indexed | 2024-12-11T07:14:32Z |
| publishDate | 2017-01-01 |
| publisher | Tehran University of Medical Sciences |
| record_format | Article |
| series | Case Reports in Clinical Practice |
| spelling | doaj.art-26400a5acd4b45f1b295d027b5d98a5d2022-12-22T01:16:16ZengTehran University of Medical SciencesCase Reports in Clinical Practice2538-26832538-26912017-01-0113Epileptic Seizure: An Atypical Presentation in BrucellosisSimin-Dokht Shoaei0Mohamad Farahbakhsh1Mehrdad Haghighi2Fahime Hadavand3Department of Infectious Diseases, Clinical Research and Development Center, Imam Hossein Hospital, ShahidBeheshti University of Medical Sciences, Tehran, IranInfectious Diseases and Tropical Medicine Research Center, School of Medicine, Shahid Beheshti University ofMedical Sciences, Tehran, IranDepartment of Infectious Diseases, Clinical Research and Development Center, Imam Hossein Hospital, ShahidBeheshti University of Medical Sciences, Tehran, IranDepartment of Infectious Diseases, Clinical Research and Development Center, Imam Hossein Hospital, ShahidBeheshti University of Medical Sciences, Tehran, IranNeurologic involvement occurs in approximately 10% cases of brucellosis and is a serious complication. It manifests with unique and some rare manifestations. We present the first patient with seizures in Brucella meningitis without encephalitis, space-occupying lesion, or vascular involvement. The patient is a 23-year-old man with complaint of seizure. He had generalized weakness for 2 weeks before. In 1st day of admission, he had the second convulsion. Cerebrospinal fluid (CSF) on admission showed lymphocytic pleocytosis and high protein. Brain magnetic resonance imaging and computed tomography scan were normal. Further evaluations resulted a positive Wright, Coombs’ Wright, and 2- mercaptoethanol (2ME) tests. Specific regimen with rifampin, doxycycline, and ceftriaxone in the 1st month then the first two with trimethoprimsulfamethoxazole (TMP-SMX) for 5 months administered. 6 months after completion of treatment in follow-up he has no seizure, systemic or localized symptoms.https://crcp.tums.ac.ir/index.php/crcp/article/view/70BrucellosisNeurobrucellosisMeningitisSeizure |
| spellingShingle | Simin-Dokht Shoaei Mohamad Farahbakhsh Mehrdad Haghighi Fahime Hadavand Epileptic Seizure: An Atypical Presentation in Brucellosis Case Reports in Clinical Practice Brucellosis Neurobrucellosis Meningitis Seizure |
| title | Epileptic Seizure: An Atypical Presentation in Brucellosis |
| title_full | Epileptic Seizure: An Atypical Presentation in Brucellosis |
| title_fullStr | Epileptic Seizure: An Atypical Presentation in Brucellosis |
| title_full_unstemmed | Epileptic Seizure: An Atypical Presentation in Brucellosis |
| title_short | Epileptic Seizure: An Atypical Presentation in Brucellosis |
| title_sort | epileptic seizure an atypical presentation in brucellosis |
| topic | Brucellosis Neurobrucellosis Meningitis Seizure |
| url | https://crcp.tums.ac.ir/index.php/crcp/article/view/70 |
| work_keys_str_mv | AT simindokhtshoaei epilepticseizureanatypicalpresentationinbrucellosis AT mohamadfarahbakhsh epilepticseizureanatypicalpresentationinbrucellosis AT mehrdadhaghighi epilepticseizureanatypicalpresentationinbrucellosis AT fahimehadavand epilepticseizureanatypicalpresentationinbrucellosis |