The Relationships between Dopaminergic, Glutamatergic, and Cognitive Functioning in 22q11.2 Deletion Syndrome: A Cross-Sectional, Multimodal <sup>1</sup>H-MRS and <sup>18</sup>F-Fallypride PET Study

The Relationships between Dopaminergic, Glutamatergic, and Cognitive Functioning in 22q11.2 Deletion Syndrome: A Cross-Sectional, Multimodal <sup>1</sup>H-MRS and <sup>18</sup>F-Fallypride PET Study

Background: Individuals with 22q11.2 deletion syndrome (22q11DS) are at increased risk of developing psychosis and cognitive impairments, which may be related to dopaminergic and glutamatergic abnormalities. Therefore, in this exploratory study, we examined the association between dopaminergic and g...

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Bibliographic Details
Main Authors: Carmen F. M. van Hooijdonk, Desmond H. Y. Tse, Julia Roosenschoon, Jenny Ceccarini, Jan Booij, Therese A. M. J. van Amelsvoort, Claudia Vingerhoets
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Genes
Subjects:
22q11.2 deletion syndrome
dopamine
glutamate
psychotic disorders
cognitive dysfunction
Online Access:https://www.mdpi.com/2073-4425/13/9/1672

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https://www.mdpi.com/2073-4425/13/9/1672

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