Genome-wide association analyses identify SPOCK as a key novel gene underlying age at menarche.

Genome-wide association analyses identify SPOCK as a key novel gene underlying age at menarche.

For females, menarche is a most significant physiological event. Age at menarche (AAM) is a trait with high genetic determination and is associated with major complex diseases in women. However, specific genes for AAM variation are largely unknown. To identify genetic factors underlying AAM variatio...

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Main Authors: Yao-Zhong Liu, Yan-Fang Guo, Liang Wang, Li-Jun Tan, Xiao-Gang Liu, Yu-Fang Pei, Han Yan, Dong-Hai Xiong, Fei-Yan Deng, Na Yu, Yin-Ping Zhang, Lei Zhang, Shu-Feng Lei, Xiang-Ding Chen, Hong-Bin Liu, Xue-Zhen Zhu, Shawn Levy, Christopher J Papasian, Betty M Drees, James J Hamilton, Robert R Recker, Hong-Wen Deng
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-03-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC2652107?pdf=render

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