Elevated ETV6 Expression in Glioma Promotes an Aggressive In Vitro Phenotype Associated with Shorter Patient Survival

Elevated ETV6 Expression in Glioma Promotes an Aggressive In Vitro Phenotype Associated with Shorter Patient Survival

<b>Background</b>: GBM astrocytes may adopt fetal astrocyte transcriptomic signatures involved in brain development and migration programs to facilitate diffuse tumor infiltration. Our previous data show that ETS variant 6 (ETV6) is highly expressed in human GBM and fetal astrocytes comp...

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Bibliographic Details
Main Authors: Zhang Xiong, Shuai Wu, Feng-jiao Li, Chen Luo, Qiu-yan Jin, Ian David Connolly, Melanie Hayden Gephart, Linya You
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Genes
Subjects:
glioblastoma
ETV6
apoptosis
proliferation
migration
invasion
Online Access:https://www.mdpi.com/2073-4425/13/10/1882

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